Bio-Inspired 3D-Printed Artificial Limb Assisting Cyborg Insects in Self-Righting Locomotion

Bio-Inspired 3D-Printed Artificial Limb Assisting Cyborg Insects in Self-Righting Locomotion

Research Background In rescue missions, to improve search and rescue efficiency, an emerging solution is the use of a combination of electronic backpacks and insects, known as cyborg insects. These insects combine the advantages of biological and electronic technologies, with additional electronic backpacks used for communication, sensing, and cont...

Trimmed Helicoids: An Architectured Soft Structure Yielding Soft Robots with High Precision, Large Workspace, and Compliant Interactions

Trimmed Helicoids: An Architectured Soft Structure Yielding Soft Robots with High Precision, Large Workspace, and Compliant Interactions

Trimming Helicoidal: A Soft Structure with High Precision, Large Workspace, and Compliant Interaction Background Introduction In recent years, inspired by biological systems, many researchers have gradually shifted from traditional rigid robot paradigms towards designs that incorporate compliant materials and structures. An elephant trunk is a typi...

Accelerating Ionizable Lipid Discovery for mRNA Delivery Using Machine Learning and Combinatorial Chemistry

Accelerating the Discovery of Ionizable Lipids for mRNA Delivery using Machine Learning and Combinatorial Chemistry Research Background To fully realize the potential of mRNA therapies, it is essential to expand the toolkit of lipid nanoparticles (LNPs). However, a key bottleneck in LNP development is identifying new ionizable lipids. Previous stud...

Elucidating Chirality Transfer in Liquid Crystals of Viruses

Study on Chirality Transfer in Liquid Crystal Viruses Chirality is a phenomenon commonly found in nature and holds significant influence in various fields such as biology, chemistry, physics, and materials science. However, the mechanism of chirality transfer from nanoscale building blocks to macroscopic helical structures remains an unsolved myste...

An Electroencephalogram Microdisplay to Visualize Neuronal Activity on the Brain Surface

An Electroencephalogram Microdisplay to Visualize Neuronal Activity on the Brain Surface

A Visualization Microdisplay for Neuronal Activity on the Brain Surface Using Electroencephalography Background Introduction Current functional mapping in neurosurgery primarily relies on verbal communication between neurosurgeons and electrophysiologists. These processes are time-consuming and have limited resolution. Additionally, the electrode g...

Volumetric Microscopy of Cerebral Arteries with a Miniaturized Optical Coherence Tomography Imaging Probe

Volumetric Microscopy of Cerebral Arteries with a Miniaturized Optical Coherence Tomography Imaging Probe

New Breakthrough in the Field of Cerebral Vascular Diseases: Clinical Application of Small Optical Coherence Tomography Imaging Probe Academic Background and Research Motivation In recent years, interventional treatment has become the preferred method for cerebrovascular diseases such as cerebral aneurysm, ischemic stroke, arterial dissection, and ...

Closed-loop Optogenetic Neuromodulation Enables High-Fidelity Fatigue-Resistant Muscle Control

Closed-loop Optogenetic Neuromodulation Enables High-Fidelity Fatigue-Resistant Muscle Control

High-Fidelity Fatigue-Resistant Muscle Control Through Closed-Loop Optogenetic Neural Modulation Background Introduction Skeletal muscle is the biological actuator for almost all movements in animals and humans. However, under various neurological conditions, the communication pathways between the central nervous system and neuromuscular components...

Simultaneous, Cortex-Wide Dynamics of Up to 1 Million Neurons Reveal Unbounded Scaling of Dimensionality with Neuron Number

Simultaneously Recording Up to a Million Neurons’ Cortical Dynamics Reveals Unbounded Scaling of Neuronal Quantity and Dimensionality Summary This scientific report titled “Simultaneously Recording Up to a Million Neurons’ Cortical Dynamics Reveals Unbounded Scaling of Neuronal Quantity and Dimensionality,” published in the journal Neuron (Volume 1...

A Magnetic Particle Imaging Approach for Minimally Invasive Imaging and Sensing with Implantable Bioelectronic Circuits

Minimally Invasive Imaging and Sensing Methods Based on Magnetic Particle Imaging and the Application of Implanted Electronic Circuits Academic Background In modern medicine, minimally invasive and biocompatible implantable bioelectronics are widely used for long-term monitoring of physiological processes inside the body. However, methods for imagi...

Semi-Supervised Thyroid Nodule Detection in Ultrasound Videos

Semi-Supervised Thyroid Nodule Detection in Ultrasound Videos

Research Report on Semi-Supervised Detection of Thyroid Nodules in Ultrasound Videos Research Background Thyroid nodules are common thyroid diseases. Early screening and diagnosis of thyroid nodules typically rely on ultrasound examinations, a common non-invasive detection method used for detecting various diseases such as thyroid nodules, breast c...