A Lactate-SREBP2 Signaling Axis Drives Tolerogenic Dendritic Cell Maturation and Promotes Cancer Progression
The Tumor Lactate-SREBP2 Signaling Pathway Drives Tolerogenic Dendritic Cell Maturation and Promotes Cancer Progression In recent years, the critical role of dendritic cells (DCs) in antitumor immunity has been widely recognized. However, many cancers cause DC dysfunction through mechanisms that are not fully understood. In a newly published study ...