This study explores the necessity of quickly recognizing and avoiding predators in the natural environment, which is crucial for juvenile animals due to their increased vulnerability to predators. However, it remains unclear whether neonatal vertebrates can rapidly acquire such skills and the underlying neural mechanisms. Zebrafish, a widely used m...

Academic Report on the Study of Layer-Specific Anatomical and Physiological Characteristics of the Retinal Neurovascular Unit Background and Problem Statement Retinal processing, similar to all neural computations, is metabolically expensive and involves the dynamic regulation of blood flow, known as neurovascular coupling (NVC). The retina is supp...

Report on the Paper “Separate Sites of Action for Cry1 and Phot1 Blue-Light Receptors in the Arabidopsis Hypocotyl” Background and Motivation Plants rely on the rapid elongation of the hypocotyl to overcome the resistance of the soil surface and access light environments for establishing autotrophic photosynthesis. Upon exposure to blue light, the ...

Highlights of the Study: Metabolite-Level Regulation of Cyanobacteria Awakening from Dormancy Study Title: “Metabolite-level regulation of enzymatic activity controls awakening of cyanobacteria from metabolic dormancy” Published in Current Biology (January 6, 2025), this study, led by Sofía Doello, involves researchers from the University of Tübing...

Report on the Study of the Impact of ANCV1R Gene Deficiency on Pheromone Detection and Sexual Behavior in Mice Background Introduction In mammals, pheromones are crucial chemical signals that regulate social and sexual behaviors. Pheromone detection is mediated by the vomeronasal organ (VNO), which uses vomeronasal sensory neurons (VSNs) to recogni...

Analysis of the Influence of Alkaloids on Frog Skin Microbiomes and Their Metabolic Functions Background and Significance Poison frogs (family Dendrobatidae) are amphibians with unique defense mechanisms, as their skin is rich in alkaloids, which are known for their broad-spectrum antimicrobial properties. However, the ways these alkaloids affect t...

Background Introduction Chemotherapy has long been a cornerstone of cancer treatment but is accompanied by significant side effects. Among cancer patients receiving platinum-based chemotherapy drugs (e.g., cisplatin), the incidence of thromboembolic events significantly increases, including pulmonary embolism, cerebrovascular incidents, angina, and...

Stage-specific Chromosomal Deletions Activate the IRX3 Oncogene in T-cell Acute Lymphoblastic Leukemia In the field of cancer research, understanding regulatory mechanisms of the noncoding genome remains a key focus, especially concerning how oncogenes can be aberrantly activated through non-canonical regulatory pathways. This paper, authored by Su...

Genetic and Pharmacological Targeting of mTORC1 in Mouse Models of Arteriovenous Malformation Expose Non-Cell Autonomous Signalling in HHT Hereditary Hemorrhagic Telangiectasia (HHT) is a genetic disorder caused by mutations leading to the loss of function in either Activin Receptor-Like Kinase 1 (ACVRL1) or Endoglin (ENG), which act as receptors a...

Academic Background Age-related macular degeneration (AMD) is a major cause of central vision loss among the elderly, particularly in its neovascular (NV) form, where choroidal neovascularization (CNV) leads to rapid and severe vision loss. Current AMD treatments primarily rely on intravitreal injections of anti-vascular endothelial growth factor (...