Research Background Glaucoma is a major cause of blindness, characterized by complex neurodegenerative conditions that include extensive inflammatory responses in glial cells, accompanied by the progressive loss of Retinal Ganglion Cells (RGCs), optic nerve axons, and synaptic connections. Although there are variations in subtypes, topologies, and ...

Protective effects of CCR5-overexpressing mesenchymal stem cells on experimental autoimmune uveitis Background Introduction Uveitis is an inflammatory eye disease that seriously threatens vision and can lead to complications such as cataracts, glaucoma, vitreous opacities, retinal detachment, and abnormal retinal vasculature. This disease is widesp...

The Key Role of Retina Microglia in Pathological Angiogenesis and the Immunotherapeutic Potential of the cGAS-STING Pathway Background Pathological angiogenesis is common in various neovascular ophthalmic diseases, such as Diabetic Retinopathy (DR) and Age-related Macular Degeneration (AMD) [1]. During these diseases, bone marrow cells, including r...

Radiation Retinopathy Research Report Radiation Retinopathy (RR) is a common side effect following radiation therapy (such as brachytherapy or proton beam therapy) in ophthalmic tumor treatments. RR presents as delayed and progressive microvascular alterations, ischemia, and macular edema, which may ultimately lead to vision loss, neovascular glauc...

Research Report on Abnormal Tau Proteins in the Retina of Alzheimer’s Disease Patients Introduction Alzheimer’s disease (AD) is the primary cause of dementia in the elderly population worldwide. The pathological features of AD include the deposition of amyloid beta-protein (Aβ) and the aggregation of abnormal microtubule-associated tau proteins in ...

Graph Theory Analysis of Brain Network Topology Structure in Patients with Primary Angle-Closure Glaucoma Research Background Glaucoma is a global blinding eye disease characterized by optic nerve damage and elevated intraocular pressure (IOP) (Kang and Tanna 2021). Among various types of glaucoma, Primary Angle-Closure Glaucoma (PACG) is particula...

Threshold and Mechanisms of Magnetophosphene Perception Background The effect of Magnetic Fields (MF) on the human body has long been a hot topic in scientific research. Extremely Low-Frequency Magnetic Fields (ELF-MF) are widespread in daily life, primarily originating from power lines (50⁄60 Hz) and household appliances. These magnetic fields can...

Academic Report on “Contralateral Delay Activity and Alpha Lateralization Reflect Retinotopic and Screen-Centered Reference Frames in Visual Memory” Introduction The visual system is organized in a lateralized manner, with the left and right visual fields processed by the contralateral cerebral cortex. This organization applies not only to percepti...

Academic Report: Research on a Biomimetic Visual Detection Model Based on Fractional Spiking Neuron Circuits In the fields of intelligent autonomous driving and unmanned aerial vehicles, quickly and effectively predicting collisions and triggering avoidance behaviors have significant application value. The Lobula Giant Movement Detectors (LGMDs) in...

Circuit Mechanisms of Hue Selectivity in the Fruit Fly Visual System Color perception is a key aspect of visual experience, playing an important role in the interaction between organisms and their environment. In primates and other animals with three types of photoreceptor cells, neurons in the visual cortex have been found to selectively respond t...