Plasma GFAP and p-tau-181 Association with Synaptic Density at 18F-SynVest-1 PET Imaging

Association of Plasma GFAP and p-tau-181 with Synaptic Density in Alzheimer’s Disease Academic Background Alzheimer’s Disease (AD) is a multifactorial neurodegenerative disorder characterized by the accumulation of amyloid-β (Aβ) plaques and tau protein aggregates in the brain. Recent research has shown that multiple factors are involved in the dev...

Aquaporin-4 Immunoglobulin G–Seropositive Neuromyelitis Optica Spectrum Disorder MRI Characteristics: Data Analysis from the International Real-World PAMRINO Study Cohort

Research Background Neuromyelitis Optica Spectrum Disorder (NMOSD) is an autoimmune central nervous system disease characterized by severe onset and relapse events, including optic neuritis, longitudinally extensive transverse myelitis (LETM), brainstem and/or hypothalamic syndromes, and encephalitis. Most patients have serum immunoglobulin G (IgG)...

Diagnostic Accuracy of Dynamic Stress Myocardial CT Perfusion in Patients with Stents: The ADVANTAGE 2 Study

Diagnostic Accuracy of Dynamic CT Perfusion in Patients with Coronary Stents Academic Background Coronary artery disease (CAD) is one of the leading causes of death worldwide. Percutaneous coronary intervention (PCI) is a common treatment for obstructive CAD. However, after stent implantation, patients may experience in-stent restenosis (ISR) or pr...

MRI-Directed Micro-US–Guided Transperineal Focal Laser Ablation for Localized Prostate Cancer: A 1-Year Follow-Up Study

MRI-Guided Micro-US Transperineal Focal Laser Ablation for Localized Prostate Cancer: A 1-Year Follow-Up Study Academic Background Prostate cancer (PCA) is one of the most common malignancies among men worldwide. With the widespread adoption of prostate-specific antigen (PSA) screening, the diagnosis of low-risk prostate cancer has significantly in...

CT-Guided Left Stellate Ganglion Cryoneurolysis for Refractory Ventricular Arrhythmias

Report on CT-Guided Left Stellate Ganglion Cryoneurolysis for Refractory Ventricular Arrhythmias Academic Background Ventricular arrhythmias (VAs), including ventricular tachycardia and ventricular fibrillation, pose a significant challenge in cardiovascular medicine due to their high morbidity, mortality, and increasing prevalence. Although curren...

Assessing Lung Ventilation and Bronchodilator Response in Asthma and Chronic Obstructive Pulmonary Disease with 19F MRI

Academic Background and Problem Statement Respiratory diseases impose a significant burden on healthcare systems globally. Although existing pulmonary function tests (such as conventional spirometry) aid in disease diagnosis and monitoring, these methods are relatively insensitive in detecting early-stage diseases and cannot provide information on ...

Low-Dose CT Screening in East Asian Women Who Have Never Smoked: Association Between Family History of Lung Cancer and Ground-Glass Nodule Prevalence and Growth

Low-Dose CT Screening in East Asian Women Who Have Never Smoked: Association Between Family History of Lung Cancer and Ground-Glass Nodule Prevalence and Growth Academic Background Lung cancer is the leading cause of cancer-related mortality worldwide, and smoking is a well-established risk factor for lung cancer. Low-dose CT (LDCT) is an effective...

Diagnostic Accuracy and Value of CXCR4-Targeted PET/MRI Using 68Ga-Pentixafor for Tumor Localization in Cushing Disease

Diagnostic Accuracy and Value of 68Ga-Pentixafor PET/MRI in Tumor Localization for Cushing’s Disease Academic Background Cushing’s disease is the primary cause of Cushing’s syndrome, characterized by excessive secretion of adrenocorticotropic hormone (ACTH) from the pituitary gland, often due to pituitary adenomas. Patients with chronic hypercortis...

Alterations in Volume and Resting-State Functional Connectivity Detected at Brain MRI in Individuals with Opioid Use Disorder

Multimodal Neuroimaging Study of Structural and Functional Brain Alterations in Individuals with Opioid Use Disorder Academic Background Opioid Use Disorder (OUD) is a complex chronic condition that has multifaceted negative impacts on an individual’s life and is closely associated with an increased risk of mortality. In 2021, over 80,000 deaths in...

MR Spectroscopy to Assess Muscle Mitochondrial Dysfunction in Long COVID

Report on the Use of MR Spectroscopy to Assess Muscle Mitochondrial Dysfunction in Long COVID Academic Background The COVID-19 pandemic has had a profound impact on global health, with many patients experiencing prolonged symptoms even after recovery, commonly referred to as “Long COVID” or “Post–COVID-19 Condition” (PCC). These symptoms include fa...