Robot-aided assessment and associated brain lesions of impaired ankle proprioception in chronic stroke

Information Science, Artificial Intelligence, Medicine, Neurology, Medical Imaging, Life Sciences, Bioengineering,
motion sense   psychometrics   proprioception   robotics   stroke  

Robot-Assisted Assessment of Chronic Stroke Adults’ Ankle Proprioception Deficits and Related Brain Injury Academic Background Stroke is a common neurological disorder, often resulting in hemiplegia, which affects the patient’s balance and gait control. Proprioception refers to the self-perception of body posture and movement, provided by mechanore...

Enhancing Fall Risk Assessment: Instrumenting Vision with Deep Learning During Walks

Information Science, Artificial Intelligence, Medicine, Neurology, Medical Imaging, Life Sciences, Bioengineering,
fall risk   gait analysis   object detection   deep learning   visual attention  

Introduction Fall events are common across various clinical populations, with usual risk assessments including visual observation of individual gait. However, gait observation assessments are typically confined to laboratory settings, involving standardized walking protocol tests to identify potential defects that might increase fall risk. Subtle d...

Automatic Gait Events Detection with Inertial Measurement Units: Healthy Subjects and Moderate to Severe Impaired Patients

Medicine, Neurology, Medical Imaging, Sports Medicine, Life Sciences, Bioengineering,
pathological gaits   gait analysis   step detection   pattern recognition   inertial measurement units   dynamic time warping  

A New Method for Automatic Gait Event Detection: Analysis of Inertial Measurement Units in Healthy Subjects and Patients with Moderate to Severe Impairment Cyril Voisard, Nicolas de L’Escalopier, Damien Ricard, Laurent Oudre. Journal of NeuroEngineering and Rehabilitation (2024) 21:104 https://doi.org/10.1186/s12984-024-01405-x Background of the St...

Impact of repetitive transcranial magnetic stimulation on cortical activity: a systematic review and meta-analysis utilizing functional near-infrared spectroscopy evaluation

Medicine, Basic Medical Sciences, Psychiatry, Neurology, Medical Imaging,
repetitive transcranial magnetic stimulation   functional near-infrared spectroscopy   primary motor cortex   cortical hemodynamics   cortical excitability  

Systematic Review and Meta-Analysis on the Impact of Repetitive Transcranial Magnetic Stimulation (rTMS) on Cortical Activity - Functional Near-Infrared Spectroscopy (fNIRS) Evaluation Background Repetitive transcranial magnetic stimulation (rTMS) is a device that induces currents within the cerebral cortex through the generation of a magnetic fiel...

Trend Change Analysis of Postural Balance in Parkinson’s Disease Discriminates Between Medication State

Medicine, Environmental and Public Health, Geriatrics, Neurology, Medical Imaging,
Parkinson's disease   Trend Change Analysis   Body Balance   Postural Stability   Balance   Wearable Sensors   Neurology  

Analysis of Trend Changes in Static Balance of Parkinson’s Disease Patients to Distinguish Drug States Introduction Maintaining static body balance is crucial for daily living, which requires coordination between different body segments. Any change or decline in balance ability increases the risk of falling. Patients with Parkinson’s disease (PD) e...

Time Synchronization Between Parietal–Frontocentral Connectivity with MRCP and Gait in Post-Stroke Bipedal Tasks

Engineering, Electrical Engineering, Information Science, Artificial Intelligence, Medicine, Neurology, Medical Imaging,
stroke   brain-computer interface   functional connectivity   motor execution   motor preparation   bipedal classification   rehabilitation  

Time Synchronization of Motor-Related Cortical Potentials and Parieto-Frontocentral Connectivity in Bilateral Tasks of Stroke Patients Background In stroke rehabilitation research, functional connectivity (FC), motor-related cortical potentials (MRCP), and gait activities are common metrics related to rehabilitation outcomes. Although these have be...

Study on the Effects of Traumatic Brain Injury on Chronic Meningeal CLIP+ B Cells, Neuropathology, and Neurobehavioral Impairment in 5xFAD Mice

Medicine, Rheumatology and Immunology, Neurology, Medical Imaging, Life Sciences, Biochemistry, Immunology,
Traumatic Brain Injury   Alzheimer's Disease   B Cells   Neuropathology   Neurobehavioral Impairment   Immune Response   5xFAD Mice  

Research Report: Long-Term Effects of Class II Invariant Peptide (CLIP) Antagonism on CLIP+ B Cells in the Meninges, Neuropathology, and Neurobehavioral Deficits in 5xFAD Mice Research Background Traumatic brain injury (TBI) is a significant public health problem affecting millions of individuals worldwide each year. More importantly, TBI is a sign...

Changes in Growth-Associated Protein 43 and Tensor-Based Morphometry Indices in Mild Cognitive Impairment

Medicine, Medical Laboratory Science, Geriatrics, Neurology, Medical Imaging,
Growth-Associated Protein 43   Alzheimer’s Disease   Tensor-Based Morphometry   Mild Cognitive Impairment   Region of Interest  

Changes in Growth-Associated Protein 43 and Tensor-Based Morphometric Indicators in Mild Cognitive Impairment Research Background Alzheimer’s disease (AD) is a globally prevalent neurodegenerative disease whose incidence is expected to increase significantly in the coming years (Esquerda-Canals et al., 2017). The disease primarily manifests as defe...

Co-registration of MALDI-MSI and histology demonstrates gangliosides co-localize with amyloid beta plaques in Alzheimer’s disease

Co-registration of MALDI-MSI and histology demonstrates gangliosides co-localize with amyloid beta plaques in Alzheimer’s disease

Medicine, Medical Laboratory Science, Neurology, Medical Imaging, Life Sciences, Biochemistry, Immunology,
Alzheimer's disease   gangliosides   lipids   MALDI-MSI   digital pathology  

Co-localization of Gangliosides with Amyloid Beta Plaques in Alzheimer’s Disease Detected by MALDI-MSI and Histology Alzheimer’s Disease (AD) is a progressive neurodegenerative disease characterized by cognitive impairment and behavioral changes. Historically, AD research has focused on misfolded proteins, but with advancements in mass spectrometry...

Associations of CSF BACE1 with Amyloid Pathology, Neurodegeneration, and Cognition in Alzheimer’s Disease

Medicine, Basic Medical Sciences, Medical Laboratory Science, Neurology, Medical Imaging, Life Sciences,
Alzheimer’s disease   BACE1   PET imaging   neurodegeneration  

Original Title: 《Associations of CSF BACE1 with Amyloid Pathology, Neurodegeneration, and Cognition in Alzheimer’s Disease》 Background and Research Purpose Alzheimer’s Disease (AD) is a leading cause of dementia in the elderly, characterized by the accumulation of β-amyloid protein (Aβ) plaques in the brain. Beta-site APP cleaving enzyme 1 (BACE1) ...