Tumor Size Is Not Everything: Advancing Radiomics as a Precision Medicine Biomarker in Oncology Drug Development and Clinical Care

In contemporary clinical oncology practice and drug development, the methods for evaluating tumor response are on the cusp of a revolution. Since the World Health Organization (WHO) proposed tumor response classification criteria for assessing the effectiveness of anti-cancer drugs in 1981, this field has undergone several improvements. Notably, th...

Circulating and Imaging Biomarkers of Radium-223 Response in Metastatic Castration-Resistant Prostate Cancer

Circulating and Imaging Biomarkers of Radium-223 Response in Metastatic Castration-Resistant Prostate Cancer

Background of Urgent Problem Prostate cancer is one of the most common cancers among men. Metastatic castration-resistant prostate cancer (mCRPC) is an advanced form of prostate cancer characterized by resistance to castration therapy. Radium-223 is an α-emitting radiopharmaceutical that has been shown to improve overall survival (OS) and reduce sk...

Towards Machine Learning-Based Quantitative Hyperspectral Image Guidance for Brain Tumor Resection

Towards Machine Learning-Based Quantitative Hyperspectral Image Guidance for Brain Tumor Resection

Study on the Role of Machine Learning-Assisted Quantitative Hyperspectral Imaging in Brain Tumor Resection Background Introduction Complete resection of malignant gliomas has always been challenged by the difficulty of distinguishing tumor cells in invasive regions. The background of this study is: In neurosurgery, the application of 5-aminolevulin...

Efficient Deep Learning-Based Automated Diagnosis from Echocardiography with Contrastive Self-Supervised Learning

Breakthrough in Automated Echocardiogram Diagnosis via Deep Learning: A Comparative Study of Self-Supervised Learning Methods Research Background With the rapid development of artificial intelligence and machine learning technologies, their role in medical imaging diagnosis is becoming increasingly significant. In particular, Self-Supervised Learni...

Precision Imaging of Cardiac Function and Scar Size in Acute and Chronic Porcine Myocardial Infarction Using Ultral-high-field MRI

Precision Imaging of Cardiac Function and Scar Size in Acute and Chronic Porcine Myocardial Infarction Using Ultral-high-field MRI

Precision Imaging of Cardiac Function and Infarct Scar Size: A Study with Ultrahigh-Field MRI in Acute and Chronic Porcine Models of Myocardial Infarction Research Background Cardiac magnetic resonance imaging (MRI) is an accurate and highly reproducible technique for assessing cardiac function and volume. In recent years, ultrahigh-field (UHF) MRI...

Improving the Segmentation of Pediatric Low-Grade Gliomas through Multitask Learning

Improved Segmentation of Pediatric Low-Grade Gliomas Through Multitask Learning Background Introduction The segmentation of pediatric brain tumors is a critical task in tumor volume analysis and artificial intelligence algorithms. However, this process is time-consuming and requires the expertise of neuroradiologists. Although significant research ...

Prediction of Glioma Grade Using Intratumoral and Peritumoral Radiomic Features from Multiparametric MRI Images

“Prediction of Glioma Grades Based on Radiomic Features Inside and Outside Tumors Using Multiparametric MRI Images” Research Background Glioma is the most common primary brain tumor in the central nervous system, accounting for 80% of adult malignant brain tumors. In clinical practice, treatment decisions often require individualized adjustments ba...

Self-Attention Similarity Guided Graph Convolutional Network for Multi-type Lower-Grade Glioma Classification Research

Self-Attention Similarity Guided Graph Convolutional Network for Multi-type Lower-Grade Glioma Classification Research

Graph Convolutional Network Based on Self-Attention Similarity for Multi-type Low-Grade Glioma Classification 1. Research Background Low-grade glioma is a common malignant brain tumor caused by the cancerous transformation of glial cells in the brain and spinal cord. Gliomas are characterized by high incidence, high recurrence rate, high mortality ...

AI-Powered Radiomics Algorithm Based on Slice Pooling for the Glioma Grading

AI-Powered Radiomics Algorithm Based on Slice Pooling for the Glioma Grading

AI-Assisted Radiomics Algorithm for Glioma Grading Based on Slice Pooling Background Introduction Glioma is the most common and threatening tumor in the central nervous system, characterized by high incidence, high recurrence rates, high mortality, and low cure rates. The World Health Organization (WHO) classifies gliomas into four grades (I, II, I...

Multimodal Disentangled Variational Autoencoder with Game Theoretic Interpretability for Glioma Grading

Application of Multi-modal Disentangled Variational Autoencoder and Game Theory Interpretability in Glioma Grading Background Gliomas are the most common primary brain tumors in the central nervous system. According to cellular activity and invasiveness, the World Health Organization (WHO) classifies them into grades I to IV, with grades I and II r...