The Effect of High Protein Dosing in Critically Ill Patients: An Exploratory, Secondary Bayesian Analyses of the EFFORT Protein Trial

Medicine, Anesthesiology,
Bayesian analysis   heterogeneity of treatment effects   intensive care   multi-organ failure   protein  

The Effect of High Protein Dosing in Critically Ill Patients: An Exploratory, Secondary Bayesian Analysis of the EFFORT Protein Trial Academic Background In the field of critical care medicine, nutritional support is a crucial component of treating critically ill patients. Protein, as a fundamental requirement for cellular function and survival, pl...

Perioperative Fluid Management: Evidence-Based Consensus Recommendations

Medicine, Anesthesiology,
perioperative   fluid management   evidence-based   consensus recommendations   surgical patients  

Perioperative Fluid Management: Evidence-Based Consensus Recommendations from the International Multidisciplinary Perioperative Quality Initiative Academic Background Perioperative fluid management is a critical component of surgical patient care, directly impacting postoperative recovery and complication rates. In recent years, with the continuous...

Human Dorsal Root Ganglia are Either Preserved or Completely Lost After Deafferentation by Brachial Plexus Injury

Medicine, Anesthesiology, Neurology,
brachial plexus injury   dorsal root ganglia   neuropathic pain   RNA-seq   sensory neurone   transcriptome   inflammation  

Paper Title: Human Dorsal Root Ganglia Are Either Preserved or Completely Lost After Deafferentation by Brachial Plexus Injury Authors: Annemarie Sodmann, Johannes Degenbeck, Annemarie Aue, Magnus Schindehütte, Felicitas Schlott, Panagiota Arampatzi, Thorsten Bischler, Max Schneider, Alexander Brack, Camelia M. Monoranu, Tom Gräfenhan, Michael Bohn...

Feasibility of Ultrasound-Guided Nerve Blocks in Simulated Microgravity: A Proof-of-Concept Study for Regional Anaesthesia During Deep Space Missions

Medicine, Anesthesiology,
microgravity   nerve block   regional anaesthesia   simulation   space medicine  

Feasibility of Ultrasound-Guided Nerve Blocks in Simulated Microgravity: A Proof-of-Concept Study for Regional Anaesthesia During Deep Space Missions Academic Background With crewed deep space exploration on the horizon, preparing for potential astronaut health crises during space missions has become a critical issue. The administration of anaesthe...

A Two-Person Verbal Check to Confirm Tracheal Intubation: Evaluation of Practice Changes to Prevent Unrecognised Oesophageal Intubation

Medicine, Anesthesiology,
tracheal intubation   oesophageal intubation   two-person check   patient safety   videolaryngoscopy   teamwork   capnography  

Background Tracheal intubation is a critical procedure in anesthesia and intensive care. However, despite international campaigns emphasizing the use of capnography to confirm tracheal intubation, unrecognized esophageal intubation continues to result in patient deaths. Esophageal intubation is an avoidable and potentially fatal complication, espec...

International Multi-Institutional External Validation of Preoperative Risk Scores for 30-Day In-Hospital Mortality in Paediatric Patients

Medicine, Pediatrics, Anesthesiology,
paediatric anaesthesia   risk prediction   external validation   mortality   preoperative scoring  

External Validation of Preoperative Risk Scores for 30-Day In-Hospital Mortality in Pediatric Patients Academic Background Although the perioperative mortality rate in pediatric patients is low (<0.5%), it remains a significant issue in clinical practice. Traditional risk assessment tools, such as the American Society of Anesthesiologists (ASA) Phy...

Effect of Perioperative Blood Transfusion on Preoperative Haemoglobin Levels as a Risk Factor for Long-Term Outcomes in Patients Undergoing Major Noncardiac Surgery: A Prospective Multicentre Observational Study

Medicine, Anesthesiology, Cardiovascular System,
perioperative transfusion   preoperative haemoglobin   long-term outcomes   noncardiac surgery   multicentre study   observational study   cardiovascular events  

Academic Background Preoperative anemia and red blood cell (RBC) transfusions are closely associated with poorer surgical outcomes. Although RBC transfusions can increase oxygen delivery, they are also linked to an increased risk of infectious complications, thromboembolic events, pneumonia, sepsis, cardiac events, and mortality. Therefore, when st...

CT-Guided Left Stellate Ganglion Cryoneurolysis for Refractory Ventricular Arrhythmias

Medicine, Anesthesiology, Medical Imaging, Cardiovascular System,
Refractory Ventricular Arrhythmias   CT-Guided   Stellate Ganglion Cryoneurolysis   Safety   Effectiveness  

Report on CT-Guided Left Stellate Ganglion Cryoneurolysis for Refractory Ventricular Arrhythmias Academic Background Ventricular arrhythmias (VAs), including ventricular tachycardia and ventricular fibrillation, pose a significant challenge in cardiovascular medicine due to their high morbidity, mortality, and increasing prevalence. Although curren...

Mechanical Ventilation Guided by Driving Pressure Optimizes Local Pulmonary Biomechanics in an Ovine Model

Engineering, Mechanical Engineering, Medicine, Respiratory System, Anesthesiology, Medical Imaging, Life Sciences, Bioengineering,
Mechanical ventilation   Driving pressure   Pulmonary biomechanics   Acute respiratory distress syndrome   Whole-lung image segmentation  

Optimization of Respiratory Pressure Under Mechanical Ventilation Guidance - A Study on Improving Local Lung Biomechanics Mechanical ventilation is commonly used in clinical practice to treat acute respiratory distress syndrome (ARDS) and prevent pulmonary complications after general anesthesia. However, mechanical ventilation can cause harmful str...

Electroencephalography-Guided Anesthesia and Delirium in Older Adults after Cardiac Surgery

Medicine, Psychiatry, Geriatrics, Anesthesiology, Neurology, Cardiovascular System,
Electroencephalography   Anesthesia   Older Adults   Cardiac Surgery   Delirium  

EEG-Guided Anesthesia and Delirium in Elderly Patients After Cardiac Surgery Research Background Delirium is a common postoperative complication in elderly patients, particularly after cardiac surgery. Delirium not only leads to cognitive decline but also increases hospitalization time and medical costs. Current preventive measures are limited in e...