Sodium Leak Channel in Glutamatergic Neurons of the Lateral Parabrachial Nucleus Helps Maintain Respiratory Rate Under Sevoflurane Anesthesia Background Respiration is a core function for maintaining life activities. General anesthetics and/or opioids often suppress respiratory function. However, the respiratory suppression caused by the intravenou...
Thalamic Reuniens Nucleus Glutamatergic Neurons Mediated Colorectal Visceral Pain in Mice through 5-HT2B Receptors Background Irritable Bowel Syndrome (IBS) is a common functional bowel disorder characterized by abdominal pain and visceral hypersensitivity. Reducing visceral hypersensitivity is crucial for effectively alleviating abdominal pain in ...
A Visualization Microdisplay for Neuronal Activity on the Brain Surface Using Electroencephalography Background Introduction Current functional mapping in neurosurgery primarily relies on verbal communication between neurosurgeons and electrophysiologists. These processes are time-consuming and have limited resolution. Additionally, the electrode g...
Research Background and Motivation Neuropathic pain is a complex and common clinical issue, accompanied by persistent spontaneous pain. Patients often report symptoms such as spontaneous pain, electric shock sensations, and burning pain. The physiological mechanisms behind this type of pain are complex, and reliable research models or biomarkers ar...
Safety and Efficacy of Intrathecal Drug Delivery Pumps for Intractable Pain in Cancer Patients Introduction Pain management in cancer patients is a critical issue in palliative care, as clinicians strive to improve patients’ quality of life and alleviate their suffering. Most cancer patients experience cancer-related pain, and 30%-40% of them suffe...
In this academic paper, the authors attempt to address the common headache complication during magnetic resonance-guided focused ultrasound (mrgFUS) treatment. Headache is a common complication, and in severe cases, it may even cause patients to be unable to tolerate ultrasound radiation and terminate the treatment. There is currently no establishe...
Outcomes of Mechanical Thrombectomy for Stroke Patients with Low Alberta Stroke Program Early CT Score Background Acute ischemic stroke is a life-threatening disease, and large vessel occlusion is one of the major causes of severe disability. Mechanical thrombectomy (MT) has become the standard treatment for acute ischemic stroke, with multiple cli...