This is a report on a new classification method for caudal agenesis: Caudal agenesis is a congenital disorder characterized by the absence of lower vertebrae. Previous classifications of caudal agenesis were primarily based on the level of bony deficiency or the position of the terminal spinal cord, but there has been debate as to whether these cla...
Correlation between Task Complexity and Accuracy of Cortical Language Mapping Introduction This study aimed to investigate whether task complexity affects the accuracy of mapping language functions during direct cortical stimulation mapping (DCS). The researchers hypothesized that due to the reduced computational ability of neurons in the cortex in...
This is a long-term outcome study on survivors of pediatric glioma. The main purpose of the study was to evaluate the impact of changes in treatment approaches for pediatric glioma over the past few decades on long-term mortality, chronic health conditions, and subsequent tumor risk among survivors. Background: In the past, treatment for pediatric ...
Meningiomas are the most common primary intracranial tumors in adults, and their incidence is rising with an aging population and the widespread use of neuroimaging examinations. While most meningiomas are benign, a small portion exhibit biological invasiveness, leading to severe neurological complications and death. In recent years, significant pr...
EDA2R Elevation in Liquid Biopsy Reflects Acute Brain Injury after Cranial Radiation Background Cranial radiation therapy is the standard treatment for advanced brain tumors and metastases, but it leads to devastating neurocognitive impairments, especially in childhood cancer survivors. As the number of childhood brain cancer survivors continues to...
Pediatric brainstem glioblastoma is the most common malignant brain tumor in children, and surgical resection is the primary treatment method. However, posterior fossa surgery may lead to a complication known as “Pediatric Cerebellar Mutism Syndrome (CMS).” CMS is primarily characterized by temporary mutism, motor disorders, and emotional abnormali...
This is a phase I clinical trial that explored the safety of preoperative single-fraction stereotactic radiosurgery (SRS) with dose escalation for patients with brain metastases. The background of this study is that for brain metastases larger than 2cm in diameter, surgery alone or single-fraction SRS alone is difficult to achieve ideal local contr...
This academic paper reports a study on exosomes in patients with glioblastoma. The study explored the potential application of exosomes as biomarkers in the diagnosis, prognosis, and treatment response monitoring of glioblastoma. Academic Background: Glioblastoma is an invasive brain tumor, and despite comprehensive treatments such as surgery, chem...
In this research paper from the journal Neuro-Oncology, the researchers investigated the relationship between the residual tumor cells at the resection margin after surgical removal and the progression-free survival (PFS) and overall survival (OS) in patients with wildtype isocitrate dehydrogenase (IDH wildtype) glioblastoma (GBM). The authors are ...
Response to First-Line Treatment of Persistent MRI Lesions in Pediatric Medulloblastoma as a Surrogate Marker for Predicting Risk of Disease Progression Medulloblastoma is one of the most common malignant central nervous system tumors in children. Although the multimodal treatment concept has significantly improved the prognosis for patients, the o...