Connectomics Reconstruction Associated with Temporal Lobe Lesions and Their Surgical Resection Academic Background The human brain’s structural organization is increasingly conceptualized and analyzed from a network perspective, greatly enhancing understanding of health and disease. In recent years, thanks to advances in neuroimaging technology and...
Low-intensity Ultrasound Promotes Brain Organoid Integration and Improves Microcephaly Defects Background of the Study Brain organoids are generated through the differentiation of pluripotent stem cells (PSCs) and exhibit impressive cellular diversity, capable of mimicking functional networks similar to the human brain. These organoid methods hold ...
Using Intracranial EEG-fMRI Mapping of Intermittent Discharges to Predict Epilepsy Surgery Outcomes Background and Objective Epilepsy is a common neurological disorder, and many patients are unresponsive to pharmacological treatments, making surgery one of the primary therapeutic options. However, accurately localizing the seizure onset zone (SOZ) ...
Epidemiological Study of Intimate Partner and Domestic Violence-Related Traumatic Brain Injuries in the United States from 2018-2021 Background Intimate partner violence (IPV) and domestic violence (DV) have severe medical, social, and legal consequences for victims. These violent events often result in traumatic brain injuries (TBIs), further exac...
Safety and Efficacy of Intrathecal Drug Delivery Pumps for Intractable Pain in Cancer Patients Introduction Pain management in cancer patients is a critical issue in palliative care, as clinicians strive to improve patients’ quality of life and alleviate their suffering. Most cancer patients experience cancer-related pain, and 30%-40% of them suffe...
Study on the Extent of Resection Threshold in Different Molecular Subtypes of Newly Diagnosed IDH-wildtype Glioblastoma Introduction Glioblastoma (GBM) is the most common malignant brain tumor in adults. Although surgical resection, radiotherapy, and chemotherapy are the current standard treatment regimens, the prognosis of GBM remains poor, with a...
This is a report on a scholarly article regarding the treatment results of low-bypass surgery for 215 patients with intracranial atherosclerotic stenosis or occlusion at Seoul National University Hospital. Background Introduction: Intracranial atherosclerotic disease (ICAD) causing stenosis or occlusion is one of the major causes leading to ischemi...
In this academic paper, the authors attempt to address the common headache complication during magnetic resonance-guided focused ultrasound (mrgFUS) treatment. Headache is a common complication, and in severe cases, it may even cause patients to be unable to tolerate ultrasound radiation and terminate the treatment. There is currently no establishe...
This is a report on the 55-year follow-up of the first case of a craniopharyngioma patient who underwent gamma knife radiosurgery. The article details the medical history, diagnosis process, gamma knife surgery details, as well as the 55-year follow-up with multiple treatments, providing a comprehensive overview of the patient’s long medical journe...
Vertebral hemangiomas are the most common primary tumors of the spine. Most vertebral hemangiomas are asymptomatic benign lesions, but in a few cases, if the mass grows and extends into the epidural space, compressing the spinal cord or nerve roots, it may lead to neurological symptoms such as pain, sensory abnormalities, or motor deficits. The tre...