Clinical Gastrointestinal Disease Screening Based on the Bionic Artificial Tentacle Method Background Gastrointestinal diseases display a wide range of complex symptoms globally, such as diarrhea, gastrointestinal bleeding, malabsorption, malnutrition, and even neurological dysfunction. These diseases pose significant health challenges and socioeco...
Neuroimaging and Molecular Markers in Alzheimer’s Disease: Data-Driven Meta-Analysis Research Background Alzheimer’s Disease (AD) is a chronic neurodegenerative disease characterized mainly by progressive memory loss and cognitive impairment, making it the most common type of dementia. Neuronal loss, one of the primary hallmarks of AD, is closely a...
Whole-Brain Mapping of Specific Orbitofrontal Cortex Neuron Inputs and Outputs in Mice Research on the mouse brain has always been an important topic in neuroscience, especially studies on the orbitofrontal cortex (ORB). The ORB plays a key role in reward processing, decision making, behavioral flexibility, and emotional regulation. In recent years...
Background Introduction The brain is composed of different subtypes of neurons, which form complex neural networks through local and long-range synaptic connections. Understanding the functions of these neural networks requires knowledge of their connection patterns (projectome) and neuronal dynamics. Although advancements in mesoscale connectomics...
Advances in Neurobiology: “Navigating” Predictable Spontaneous Brain States through Cognitive Maps Background Introduction Spontaneous brain activity refers to brain processes that are not constrained by specific inputs or outputs, and these processes play an important role in neural and cognitive variability. Although the specific mechanisms of sp...
Mesoscale Organization of Ventral and Dorsal Visual Pathways in Macaque Monkey Revealed by 7T fMRI In the journal Progress in Neurobiology, a research team from the Interdisciplinary Institute of Neuroscience and Technology and the Department of Neurosurgery at the Second Hospital in Zhejiang University published a paper titled “Mesoscale organizat...
Analyzing the Gene Expression Network in Developing Hippocampus from the Perspective of NEIL3 Deficiency Background The hippocampus, a crucial region of the brain, is well-regarded for its key roles in memory consolidation, information processing, and emotional regulation. In the field of neuroscience research, the gene regulatory mechanisms of the...
Epilepsy is one of the most common neurological disorders, with temporal lobe epilepsy (TLE) being the most prevalent form of drug-resistant epilepsy in adults. Numerous studies have indicated that TLE involves not only pathological changes in the medial temporal lobe but also affects widespread brain structures and functions. In this scientific re...
Major Breakthrough in Brain Science: Multimodal MRI Reveals Brainstem Connectivity Maintaining Human Consciousness and Wakefulness Background Introduction Consciousness comprises two fundamental components: wakefulness and awareness. Despite significant progress in understanding the cortical networks related to consciousness over the past two decad...
New Breakthrough in the Field of Cerebral Vascular Diseases: Clinical Application of Small Optical Coherence Tomography Imaging Probe Academic Background and Research Motivation In recent years, interventional treatment has become the preferred method for cerebrovascular diseases such as cerebral aneurysm, ischemic stroke, arterial dissection, and ...