An Explicit Estimated Baseline Model for Robust Estimation of Fluorophores Using Multiple-Wavelength Excitation Fluorescence Spectroscopy

Research Background Fluorescence spectroscopy is a widely used method for identifying and quantifying fluorescent substances (fluorophores). However, quantifying the fluorophores of interest becomes challenging when the material contains other fluorophores (baseline fluorophores), especially when the emission spectrum of the baseline is not well-de...

Multi-Level Feature Exploration and Fusion Network for Prediction of IDH Status in Gliomas from MRI

Multi-Level Feature Exploration and Fusion Network for Prediction of IDH Status in MRI Background Glioma is the most common malignant primary brain tumor in adults. According to the 2021 World Health Organization (WHO) classification of tumors, genotype plays a significant role in the classification of tumor subtypes, especially the isocitrate dehy...

Normalizing Flow-Based Distribution Estimation of Pharmacokinetic Parameters in Dynamic Contrast-Enhanced Magnetic Resonance Imaging

In modern medical diagnostics and clinical research, Dynamic Contrast-Enhanced Magnetic Resonance Imaging (DCE-MRI) technology provides significant information regarding tissue pathophysiology. By fitting a Tracer-Kinetic (TK) model, pharmacokinetic (PK) parameters can be extracted from time-series MRI signals. However, these estimated PK parameter...

A Siamese-Transport Domain Adaptation Framework for 3D MRI Classification of Gliomas and Alzheimer’s Diseases

Classification of 3D MRI Gliomas and Alzheimer’s Disease Based on the Siamese-Transport Domain Adaptation Framework Background In computer-aided diagnosis, 3D magnetic resonance imaging (MRI) screening plays a vital role in the early diagnosis of various brain diseases, effectively preventing the deterioration of the condition. Glioma is a common m...

Vision Transformers, Ensemble Model, and Transfer Learning Leveraging Explainable AI for Brain Tumor Detection and Classification

In recent years, due to the high incidence and lethality of brain tumors, rapid and accurate detection and classification of brain tumors have become particularly important. Brain tumors include both malignant and non-malignant types, and their abnormal growth can cause long-term damage to the brain. Magnetic Resonance Imaging (MRI) is a commonly u...

Evaluating the Predictive Value of Glioma Growth Models for Low-Grade Glioma after Tumor Resection

Research Review on the Predictive Value of Low-Grade Glioma Postoperative Growth Models Introduction Glioma is an aggressive brain tumor whose cells rapidly diffuse within the brain. Understanding and predicting the pattern and speed of this diffusion can help optimize treatment plans. Glioma growth models based on diffusion-proliferation have show...

Physics-Informed Deep Learning for Musculoskeletal Modeling: Predicting Muscle Forces and Joint Kinematics from Surface EMG

Musculoskeletal models have been widely used in biomechanical analysis because they can estimate motion variables that are difficult to measure directly in living organisms, such as muscle forces and joint moments. Traditional physics-driven computational musculoskeletal models can explain the dynamic interactions between neural inputs to muscles, ...

Uncovering the Neural Mechanisms of Inter-Hemispheric Balance Restoration in Chronic Stroke through EMG-Driven Robot Hand Training: Insights from Dynamic Causal Modeling

Uncovering the Neural Mechanisms of Inter-Hemispheric Balance Restoration in Chronic Stroke through EMG-Driven Robot Hand Training: Insights from Dynamic Causal Modeling

Revealing the Neuromechanism of Interhemispheric Balance Restoration in Chronic Stroke Patients through EMG-driven Robot Hand Training: Insights from Dynamic Causal Modeling Stroke is a common cause of disability, with most stroke survivors suffering from upper limb paralysis. The consequences of upper limb functional impairment can persist for ove...

Wavelet-Based Temporal-Spectral-Attention Correlation Coefficient for Motor Imagery EEG Classification

Brain-Computer Interface (BCI) technology has rapidly developed in recent years and is considered a cutting-edge technology that allows external devices to be controlled directly by the brain without the need for peripheral nerves and muscles. Particularly in the application of Motor Imagery Electroencephalography (MI-EEG), BCI technology has shown...

Magnetoencephalography-Derived Oscillatory Microstate Patterns Across Lifespan: The Cambridge Centre for Ageing and Neuroscience Cohort

Application of Magnetoencephalography (MEG) to Analyze Changes in Whole-Brain Oscillatory Microstate Patterns Across the Lifespan: Cambridge Centre for Aging and Neuroscience Cohort Study Research Background With the increasing seriousness of the aging population problem, understanding the neurophysiological changes during the aging process becomes...