Intensity Score of Vessel Wall Contrast Enhancement in MRI Allows Prediction of Disease Progression in Moyamoya Angiopathy

Intensity Score of Vessel Wall Contrast Enhancement in MRI Allows Prediction of Disease Progression in Moyamoya Angiopathy

This study explored the value of arterial wall enhancement grading on magnetic resonance imaging in predicting disease progression of moyamoya disease. This was a single-center retrospective cohort study that included 48 patients diagnosed with moyamoya disease who underwent arterial wall imaging and digital subtraction angiography follow-up. The s...

Scalp nerve block alleviates headaches associated with sonication during transcranial magnetic resonance–guided focused ultrasound

In this academic paper, the authors attempt to address the common headache complication during magnetic resonance-guided focused ultrasound (mrgFUS) treatment. Headache is a common complication, and in severe cases, it may even cause patients to be unable to tolerate ultrasound radiation and terminate the treatment. There is currently no establishe...

Outcomes of Mechanical Thrombectomy for Patients with Stroke Presenting with Low Alberta Stroke Program Early Computed Tomography Score in Early and Late Time Windows

Outcomes of Mechanical Thrombectomy for Stroke Patients with Low Alberta Stroke Program Early CT Score Background Acute ischemic stroke is a life-threatening disease, and large vessel occlusion is one of the major causes of severe disability. Mechanical thrombectomy (MT) has become the standard treatment for acute ischemic stroke, with multiple cli...

Hyperbolic secant representation of the logistic function: Application to probabilistic multiple instance learning for CT intracranial hemorrhage detection

There has long been a problem of “weak supervision” in the field of artificial intelligence, where only part of the labels are observable in the training data, while the remaining labels are unknown. Multiple Instance Learning (MIL) is a paradigm to address this issue. In MIL, the training data is divided into multiple “bags”, each containing multi...

Abnormal Functional Connectivity in Brain Regions of Cerebellar Mutism Syndrome Patients After Chemotherapy

Pediatric brainstem glioblastoma is the most common malignant brain tumor in children, and surgical resection is the primary treatment method. However, posterior fossa surgery may lead to a complication known as “Pediatric Cerebellar Mutism Syndrome (CMS).” CMS is primarily characterized by temporary mutism, motor disorders, and emotional abnormali...

Phase I Trial of Dose Escalation for Preoperative Stereotactic Radiosurgery for Patients with Large Brain Metastases

This is a phase I clinical trial that explored the safety of preoperative single-fraction stereotactic radiosurgery (SRS) with dose escalation for patients with brain metastases. The background of this study is that for brain metastases larger than 2cm in diameter, surgery alone or single-fraction SRS alone is difficult to achieve ideal local contr...

Circulating Extracellular Vesicles as Biomarker for Diagnosis, Prognosis and Monitoring in Glioblastoma Patients

This academic paper reports a study on exosomes in patients with glioblastoma. The study explored the potential application of exosomes as biomarkers in the diagnosis, prognosis, and treatment response monitoring of glioblastoma. Academic Background: Glioblastoma is an invasive brain tumor, and despite comprehensive treatments such as surgery, chem...

Treatment response as surrogate to predict risk for disease progression in pediatric medulloblastoma with persistent MRI lesions after first-line treatment

Response to First-Line Treatment of Persistent MRI Lesions in Pediatric Medulloblastoma as a Surrogate Marker for Predicting Risk of Disease Progression Medulloblastoma is one of the most common malignant central nervous system tumors in children. Although the multimodal treatment concept has significantly improved the prognosis for patients, the o...