The Cortical Neurophysiological Signature of Amyotrophic Lateral Sclerosis

Analysis of Cortical Neurophysiological Characteristics of ALS and Its Potential as a Biomarker Background Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disease that affects adults, characterized by a gradual loss of the integrity of the brain, spinal cord, and peripheral motor system. Although clinical and genetic studies have reveale...

Neural Representations of Perspectival Shapes and Attentional Effects: Evidence from fMRI and MEG

Neural Representation of Perspective Shapes and the Effect of Attention: Evidence from fMRI and MEG Introduction We always perceive objects from a specific perspective. In many cases, the shape we rely on when observing an object, the perspective shape, differs from its objective shape, the physical shape in the real world. For instance, a coin rot...

Tracking the Neurodevelopmental Trajectory of Beta Band Oscillations with Optically Pumped Magnetometer-based Magnetoencephalography

Tracking the Neurodevelopmental Trajectory of Beta Band Oscillations with Optically Pumped Magnetometer-based Magnetoencephalography

Research Background Neural oscillations are fundamental components of brain function, coordinating electrophysiological activities within and between neural assemblies, which is crucial for cognitive and behavioral processes. During children’s growth, the development of these neural processes is not only an important neuroscience issue but also can...

Somatosensory Evoked Spikes in Normal Adults Detected by Magnetoencephalography

Somatosensory Evoked Spikes in Normal Adults Detected by Magnetoencephalography Research Background and Motivation Since 1949, clinical neurophysiology research has discovered that high-voltage cortical somatosensory evoked potentials (SEPs) can be detected in patients with reflex epilepsy, where seizures are triggered by somatosensory stimulation ...

Spatiotemporal Brain Hierarchies of Auditory Memory Recognition and Predictive Coding

Spatiotemporal Brain Hierarchies of Auditory Memory Recognition and Predictive Coding

The Spatiotemporal Hierarchical Structure of the Brain in Auditory Memory Recognition and Predictive Coding Background This study aims to explore the hierarchical brain mechanisms involved in human identification of previously memorized music sequences and their systematic changes. While extensive research has been conducted on neural processing of...

Post-Task Responses Following Working Memory and Movement Are Driven by Transient Spectral Bursts with Similar Characteristics

Background and Research Questions Working memory and post-task responses (PTRs) in the brain have been a focal point in neuroscience research. Previous studies have shown that post-movement beta rebound (PMBR) is a reliable and stable phenomenon in the cerebral cortex that can be studied and measured using magnetoencephalography (MEG). Recent resea...

Four-Channel Optically Pumped Magnetometer for a Magnetoencephalography Sensor Array

Four-Channel Optically Pumped Magnetometer for a Magnetoencephalography Sensor Array

Four-Channel Optically Pumped Magnetometer for MEG Sensor Arrays Background Optically Pumped Magnetometers (OPMs) operating in the Spin-Exchange Relaxation-Free (SERF) regime are highly sensitive magnetic field sensors, with sensitivities as low as 0.16 ft/√Hz and 0.54 ft/√Hz. OPMs are based on the interaction between spin-polarized atoms and magne...

Human Sensorimotor Resting State Beta Events and Aperiodic Activity Show Good Test–Retest Reliability

Human Sensorimotor Resting State β Events and Aperiodic Activity Exhibit Good Test-Retest Reliability Background Neurological diseases are some of the most impactful diseases on daily human life, particularly those affecting sensory and motor functions, such as Parkinson’s disease. Early diagnosis of these diseases is often exceedingly difficult du...

Spatiotemporal Dynamics of Cortical Somatosensory Network in Typically Developing Children

Temporal and Spatial Dynamics of Somatosensory Cortex Network in Typically Developing Children Research Background Touch plays a crucial role in our interaction with external objects and the fine control of hand movements. Despite substantial research on the mechanisms of sensory information processing in human skin, it remains unclear how brain re...

Measuring Human Auditory Evoked Fields with a Flexible Multi-Channel OPM-Based MEG System

Measuring Human Auditory Evoked Fields with a Flexible Multi-Channel OPM-Based MEG System

Measurement of Human Auditory Evoked Fields Using a Flexible Multichannel Optically Pumped Magnetometer MEG System Xin Zhang and others, from the Suzhou Institute of Biomedical Engineering and Technology of the Chinese Academy of Sciences, University of Science and Technology of China, Jihua Laboratory in Foshan, Guangdong Province, and Guoke Medic...