Neural Basis of Categorical Representations of Animal Body Silhouettes

Neural Mechanism | Neural Basis of Animal Body Silhouette Classification This article, written by Yue Pu and Shihui Han, published in “neurosci. bull.” in 2024, explores the neural processes of rapid classification and cognition of animal body silhouettes in humans. The study aims to reveal how humans identify and categorize individuals of differen...

Cortical Morphological Networks Differ Between Gyri and Sulci

Differences in Brain Cortical Morphological Networks Between Gyri and Sulci Introduction The human brain, as an interconnected complex network, can be mapped through virtual imaging using multimodal magnetic resonance imaging (MRI) technology. By analyzing this network using graph theory methods, many studies have discovered some non-trivial topolo...

Fluoxetine Rescues Excessive Myelin Formation and Psychological Behaviors in a Murine PTSD Model

Fluoxetine Rescues Excessive Myelin Formation and Psychological Behaviors in a Murine PTSD Model Background Post-traumatic stress disorder (PTSD) is a complex mental disorder characterized by spontaneous intrusions of traumatic memories, avoidance of trauma-related stimuli, negative emotions and cognitions, and hyperarousal. Although existing first...

Serum LDL Promotes Microglial Activation and Exacerbates Demyelinating Injury in Neuromyelitis Optica Spectrum Disorder

Study on Serum LDL Promoting Microglial Activation and Exacerbating Demyelination in Neuromyelitis Optica Spectrum Disorder Neuromyelitis Optica Spectrum Disorder (NMOSD) is an autoimmune inflammatory demyelinating disease of the central nervous system (CNS), often accompanied by disruption of the blood-brain barrier (BBB). Dysfunction of lipid met...

Nucleus Accumbens Corticotropin-Releasing Hormone Neurons Projecting to the Bed Nucleus of the Stria Terminalis Promote Wakefulness and Positive Affective State

Nucleus Accumbens Corticotropin-Releasing Hormone Neurons Project to Bed Nucleus of the Stria Terminalis to Regulate Wakefulness and Positive Emotional States Background The nucleus accumbens (NAc) plays a crucial role in regulating motivation, reward, and many behaviors that depend on high levels of arousal. However, research on the neural mechani...

Low-Frequency Stimulation at the Subiculum Prevents Extensive Secondary Epileptogenesis in Temporal Lobe Epilepsy

In the field of neuroscience, epilepsy has always been a disease of great concern, with significant challenges remaining in clinical research and treatment. Among these, the issue of secondary epileptogenesis has had a profound impact on academia and clinical treatment. Secondary epileptogenesis refers to the continuous spread of epileptic activity...

The Role of Occipitotemporal Network for Speed-Reading: An fMRI Study

The Role of Occipitotemporal Network for Speed-Reading: An fMRI Study

The Role of Occipitotemporal Network in Rapid Reading - An fMRI-based Study Background Reading is the most effective cognitive means for humans to acquire new knowledge. Although most native English-speaking adults read at an average speed of about 200 to 400 words per minute (w/min), many people hope to increase their reading speed to acquire new ...

Distinct Contributions of Alpha and Beta Oscillations to Context-Dependent Visual Size Perception

Revealing Different Cognitive Mechanisms of the Ebbinghaus Illusion Through Neural Oscillations Academic Background Human perception of size in vision is not entirely faithful to the physical world and is highly dependent on context. For example, when an object is surrounded by several smaller objects, it appears larger than when surrounded by larg...

The Chemokine CCL2 Promotes Excitatory Synaptic Transmission in Hippocampal Neurons via GluA1 Subunit Trafficking

In the latest research paper “Chemokine CCL2 Promotes Excitatory Synaptic Transmission in Hippocampal Neurons via GluA1 Subunit Trafficking” published in “Neurosci. Bull.”, researchers from multiple institutions, including the Shanghai Institute of Neuroscience, Chinese Academy of Sciences, and the School of Life Sciences, Peking University, have d...

Gating of social behavior by inhibitory inputs from hippocampal CA1 to retrosplenial agranular cortex

Gating of Social Behavior by Inhibitory Input from Hippocampal CA1 to Retrosplenial Agranular Cortex Background Social behavior is a fundamental requirement for mammalian survival and reproduction, requiring the perception of sensory information, processing of social relevance, and further integration in the prefrontal cortex. Neuropsychiatric diso...