Inferring Latent Neural Circuits from Heterogeneous Neural Responses During Cognitive Tasks Academic Background In cognitive tasks, higher cortical areas of the brain (such as the prefrontal cortex, PFC) are responsible for integrating a variety of sensory, cognitive, and motor signals. However, the responses of individual neurons often exhibit com...
Separating Cognitive and Motor Processes: A Breakthrough in Mouse Behavioral Research Academic Background In the study of animal behavior, cognitive processes and motor processes are often closely intertwined. For example, when a mouse explores its environment, its facial expressions or active sampling behaviors not only reflect movement but are al...
Exploration of the Architecture of the Human Default Mode Network: A Study Based on Cytoarchitecture, Wiring, and Signal Flow Academic Background The Default Mode Network (DMN) is a set of brain regions that are highly active during resting states, primarily distributed across the frontal, temporal, and parietal lobes. The DMN plays a crucial role ...
Cell-Type Classification of Psychiatric Disorders: New Study Reveals Cellular Basis of Schizophrenia and Other Complex Brain Disorders Academic Background Psychiatric disorders, such as schizophrenia, depression, and bipolar disorder, are significant public health issues worldwide. These disorders are typically caused by a combination of multiple g...
Neural Mechanisms of Visual Perception and Motor Coordination Academic Background In daily life, animals need to distinguish sensory experiences caused by the external environment from those elicited by their own movements. This distinction is crucial for accurate perception and motor control. However, the diversity of behaviors and their complex i...
Retrieval of Conditioned Immune Response in Mice is Mediated by an Anterior-Posterior Insular Circuit Academic Background The bidirectional relationship between the brain and the immune system is a cornerstone of philosophical and scientific research. In recent years, researchers have identified multiple pathways through which the immune system inf...
The Formation of Reliable Representations in Visual Cortex Development Academic Background The development of the visual cortex is a significant area of research in neuroscience. In early development, the network structure of the visual cortex has already formed, but how these networks respond to the onset of visual experience and ultimately form m...
Study on the Propagation of Neuronal Micronuclei Regulating Microglial Characteristics Academic Background Microglia, the resident immune cells in the central nervous system (CNS), play a crucial role in maintaining brain homeostasis, regulating neuronal development, synaptic pruning, and responding to pathological states. However, despite extensiv...
Temporal Dynamics Constraints on Neural Population Activity: Computational Mechanisms of Neural Activity Revealed by Brain-Computer Interfaces Academic Background How neural activity in the brain evolves over time is a central issue in understanding sensory, motor, and cognitive functions. For a long time, network models have posited that the brain...
New Discoveries in Astrocyte Regulation of Behavior: Application of the AstroLight Tool Academic Background For a long time, neuroscience research has primarily focused on neuronal activity, while neglecting the role of astrocytes in brain function. Although astrocytes are one of the most numerous cell types in the brain, they have traditionally be...