Utilizing fMRI to Guide TMS Targets: The Reliability and Sensitivity of fMRI Metrics at 3T and 1.5T

Utilizing fMRI to Guide TMS Targets: The Reliability and Sensitivity of fMRI Metrics at 3T and 1.5T

Using fMRI to Guide TMS Target Selection: Reliability and Sensitivity of 3T and 1.5T fMRI Metrics [DOI: 10.1007/s12021-024-09667-5], published in Neuroinformatics Background Introduction The early application of functional magnetic resonance imaging (fMRI) mainly focused on inferring cognitive processes. However, modern medicine is gradually extend...

Investigating the impact of poverty on mental illness in the UK Biobank using Mendelian randomization

Study on the Impact of Poverty on Mental Illness: A Mendelian Randomization Analysis Based on the UK Biobank This article aims to explore the causal relationship between poverty and mental illness. Although many studies have shown an association between low socioeconomic status and mental illnesses, most studies have failed to determine whether pov...

Identifying behaviour-related and physiological risk factors for suicide attempts in the UK Biobank

Research Background: Suicide is a global public health challenge, but there is still significant uncertainty regarding the relationship between behavioral and physiological factors and suicide attempts (SA). Previous studies often focus on limited hypothesized factors such as mental illnesses (e.g., depression), personality and psychological traits...

The Necessity of Human Ventromedial Prefrontal Cortex in Prosocial Motivation

The Necessity of the Human Ventromedial Prefrontal Cortex for Prosocial Motivation Research Background and Motivation The ventromedial prefrontal cortex (vmPFC) plays a crucial role in decision-making processes. Functional neuroimaging studies indicate that the vmPFC is key in handling rewards and efforts and is also associated with prosocial behav...

Brain mechanisms underlying the emotion processing bias in treatment-resistant depression

Brain Mechanism Study on Emotion Processing Bias in Patients with Highly Treatment-Resistant Depression Background Introduction Depression is one of the mental diseases prevalent in modern society that severely affect individuals’ physical and mental health. According to Beck’s cognitive model, the development and maintenance of depression are larg...

Cortical Gene Expression Architecture links Healthy Neurodevelopment to the Imaging, Transcriptomics and Genetics of Autism and Schizophrenia

Research Report: The Connection Between Cortical Gene Expression and Neurodevelopmental Disorders Research Background The anatomical and functional organization of the human brain is the result of the coordinated expression of numerous genes. It has been found that the first principal component (c1) of cortical gene expression plays a significant r...

Gamma Oscillations of Visual Cortex Underlying Emotion and Cognition Deficits Associated with Suicide Attempt in Major Depressive Disorder

Research on Gamma Oscillations Related to Suicidal Behavior in Patients with Depression Introduction Suicide is one of the most severe human behaviors globally, particularly prevalent among patients with Major Depressive Disorder (MDD). Studies have shown that nearly half of those who die by suicide had been diagnosed with MDD. Despite its signific...

k-emophone: a mobile and wearable dataset with in-situ emotion, stress, and attention labels

Scientific Data Report | K-emophone: A Mobile and Wearable Dataset with On-site Emotion, Stress, and Attention Labels Background With the proliferation of low-cost mobile and wearable sensors, numerous studies have leveraged these devices to track and analyze human mental health, productivity, and behavioral patterns. However, despite the developme...

Modulating the Difficulty of a Visual Oddball-like Task and P3m Amplitude

Modulation of P3m Amplitude by Task Difficulty in a Visual Oddball Task Background In cognitive neuroscience research, Event-Related Potentials (ERP) and Event-Related Fields (ERF) are important means to explore the cognitive processing mechanisms of the brain. Among these, the P3 component (referred to as P3m in magnetoencephalography) has garnere...

Macroscale Intrinsic Dynamics are Associated with Microcircuit Function in Focal and Generalized Epilepsies

Macroscale Intrinsic Dynamics are Associated with Microcircuit Function in Focal and Generalized Epilepsies

Study on the Relationship between Macroscopic Intrinsic Dynamics and Microcircuit Functions in Epilepsy Research Background Epilepsy is a group of neurological disorders characterized by abnormal spontaneous brain activity, involving multi-scale changes in brain functional organization. However, it remains unclear to what extent epilepsy-related sp...