Longitudinal Associations Between Time Perspective and Life Satisfaction Across Adulthood

Research Report on the Long-term Relationship between Time Perspective and Life Satisfaction in Adulthood Research Background Time perspective is an important predictor of human well-being. However, time perspective itself changes with development. A future-dominated time perspective gradually gives way to a present and past-focused perspective as ...

Influence of Virtual Reality and Task Complexity on Digital Health Metrics Assessing Upper Limb Function

A Study Report on the Impact of Task Complexity on Digital Health Metrics Evaluation of Upper Limb Function Research Background In patients with neurological diseases such as multiple sclerosis (PWMS), the prevalent upper limb dysfunction significantly affects the completion of daily living activities, increasing dependence on caregivers. To enhanc...

A Scoping Review on Examination Approaches for Identifying Tactile Deficits at the Upper Extremity in Individuals with Stroke

Academic Report on “The Scope Review of Upper Limb Tactile Deficit Examination Methods” In recent years, post-stroke patients’ capacity to perceive tactile stimuli has become a focal point of research. This perception is very important for the execution of movements and learning activities in everyday life. However, tactile perceptual deficits seri...

Impact of repetitive transcranial magnetic stimulation on cortical activity: a systematic review and meta-analysis utilizing functional near-infrared spectroscopy evaluation

Systematic Review and Meta-Analysis on the Impact of Repetitive Transcranial Magnetic Stimulation (rTMS) on Cortical Activity - Functional Near-Infrared Spectroscopy (fNIRS) Evaluation Background Repetitive transcranial magnetic stimulation (rTMS) is a device that induces currents within the cerebral cortex through the generation of a magnetic fiel...

Intermittent Hypoxia Exacerbates Anxiety in High-fat Diet-Induced Diabetic Mice by Inhibiting TREM2-Regulated IFNAR1 Signaling

Over the past few decades, the incidence of type 2 diabetes mellitus (T2DM) has been on the rise, becoming a global public health issue. T2DM not only affects patients’ metabolic levels but also has profound impacts on cognitive function and mental health. Studies have shown that patients with T2DM exhibit brain structural abnormalities, a decline ...

Microglial PDCD4 Deficiency Mitigates Neuroinflammation-Associated Depression via Facilitating Daxx Mediated PPARγ/IL-10 Signaling

Deletion of Microglia PDCD4 Alleviates Neuroinflammation-Associated Depression by Promoting DAXX-Mediated PPARγ/IL-10 Signaling Background In recent years, neuroinflammatory processes have been demonstrated to be associated with various psychiatric disorders, including schizophrenia, depression, and anxiety. A common feature of these diseases is th...

Impaired GABAergic Regulation and Developmental Immaturity in Interneurons Derived from the Medial Ganglionic Eminence in the Tuberous Sclerosis Complex

Hippocampal Neurons - The Destructive Force Behind Epilepsy and Mental Disorders Background Introduction Tuberous Sclerosis Complex (TSC) is a complex multi-system genetic disorder that manifests with lesions in the brain, skin, heart, kidneys, and other organs as the patient ages. Clinically, TSC presents with symptoms such as epilepsy and develop...

Identifying Diagnostic Biomarkers for Autism Spectrum Disorder Using the PED Algorithm

Identifying Diagnostic Biomarkers for Autism Spectrum Disorder Using the PED Algorithm

Identifying Diagnostic Biomarkers for Autism Spectrum Disorder using the PED Algorithm In the field of neuroinformatics, research on Autism Spectrum Disorder (ASD) predominantly focuses on the bidirectional connectivity between brain regions, with fewer studies addressing higher-order interaction anomalies among brain regions. To explore the comple...

Utilizing fMRI to Guide TMS Targets: The Reliability and Sensitivity of fMRI Metrics at 3T and 1.5T

Utilizing fMRI to Guide TMS Targets: The Reliability and Sensitivity of fMRI Metrics at 3T and 1.5T

Using fMRI to Guide TMS Target Selection: Reliability and Sensitivity of 3T and 1.5T fMRI Metrics [DOI: 10.1007/s12021-024-09667-5], published in Neuroinformatics Background Introduction The early application of functional magnetic resonance imaging (fMRI) mainly focused on inferring cognitive processes. However, modern medicine is gradually extend...

Investigating the impact of poverty on mental illness in the UK Biobank using Mendelian randomization

Study on the Impact of Poverty on Mental Illness: A Mendelian Randomization Analysis Based on the UK Biobank This article aims to explore the causal relationship between poverty and mental illness. Although many studies have shown an association between low socioeconomic status and mental illnesses, most studies have failed to determine whether pov...