Post-Task Responses Following Working Memory and Movement Are Driven by Transient Spectral Bursts with Similar Characteristics

Background and Research Questions Working memory and post-task responses (PTRs) in the brain have been a focal point in neuroscience research. Previous studies have shown that post-movement beta rebound (PMBR) is a reliable and stable phenomenon in the cerebral cortex that can be studied and measured using magnetoencephalography (MEG). Recent resea...

GCTNet: A Graph Convolutional Transformer Network for Major Depressive Disorder Detection Based on EEG Signals

GCTNet: Graph Convolution Transformer Network for Detecting Major Depressive Disorder Based on EEG Signals Research Background Major Depressive Disorder (MDD) is a prevalent mental illness characterized by significant and persistent low mood, affecting over 350 million people worldwide. MDD is one of the leading causes of suicide, resulting in appr...

The Effect of TDCS on Inhibitory Control and its Transfer Effect on Sustained Attention in Children with Autism Spectrum Disorder: An fNIRS Study

The Effect of TDCS on Inhibitory Control and Its Transfer Effect on Sustained Attention in Children with Autism Spectrum Disorder: An fNIRS Study Background Autism Spectrum Disorder (ASD) is a type of neurodevelopmental disorder characterized by social communication impairments, narrow interests, and repetitive behaviors. Many studies have found th...

Intensity-Dependent Effects of TDCS on Motor Learning Are Related to Dopamine

The Intensity-Dependent Effects of Cortical Electrical Stimulation on Motor Learning and the Role of Dopamine Background Introduction Nowadays, non-invasive brain stimulation techniques such as transcranial direct current stimulation (tDCS) are widely used in neuroplasticity research to modulate cognition and behavior. However, optimizing stimulati...

Treadmill Exercise Reshapes Cortical Astrocytic and Neuronal Activity to Improve Motor Learning Deficits Under Chronic Alcohol Exposure

Background and Research Motivation Alcohol abuse is a global health issue, affecting over 8% of the male population. Prolonged alcohol exposure can alter the homeostasis of neurons and synapses in the brain, leading to various mental disorders and cognitive deficits, especially in motor learning. Previous studies have shown that alcohol abuse cause...

Predictable Navigation through Spontaneous Brain States with Cognitive-Map-Like Representations

Predictable Navigation through Spontaneous Brain States with Cognitive-Map-Like Representations

Advances in Neurobiology: “Navigating” Predictable Spontaneous Brain States through Cognitive Maps Background Introduction Spontaneous brain activity refers to brain processes that are not constrained by specific inputs or outputs, and these processes play an important role in neural and cognitive variability. Although the specific mechanisms of sp...

Phase of Neural Oscillations as a Reference Frame for Attention-Based Routing in Visual Cortex

Phase of Neural Oscillations as a Reference Frame for Attention-Based Routing in Visual Cortex

One of the key issues in understanding the visual system’s selective attention is how it optimizes the perception and processing of visual information in specific behavioral contexts. Although previous research has analyzed the pivotal role of individual neuron firing rates in information transmission, our understanding remains limited regarding ho...

Accumulation of NMDA Receptors in Accumbal Neuronal Ensembles Mediates Increased Conditioned Place Preference for Cocaine After Prolonged Withdrawal

Study Reveals Molecular Mechanisms of Enhanced Cocaine Craving in Rats During Withdrawal Background Introduction The issue of relapse in drug abuse poses a significant challenge in addiction treatment. According to related research, relapse behaviors in drug addiction are often triggered by environmental cues associated with drug use. This phenomen...

Central C3a Receptor Modulates LPS-Induced Depressive-like Behaviors

The Regulatory Mechanism of Central Complement C3a Receptor on LPS-Induced Depressive-Like Behavior Introduction With the increasing number of depression patients globally, major depressive disorder (MDD) has become one of the leading causes of disability worldwide. The symptoms, treatment effects, and biological correlations of depression exhibit ...

Transcriptomic Sex Differences in Postmortem Brain Samples from Patients with Psychiatric Disorders

Transcriptomic Sex Differences in Postmortem Brain Samples from Patients with Psychiatric Disorders

Analysis of Gender Differences in Transcriptomes of Postmortem Brain Tissues from Psychiatric Patients Background Gender differences in psychiatric patients are a well-documented phenomenon. Disorders such as Schizophrenia (SCZ), Bipolar Disorder (BD), and Autism Spectrum Disorder (ASD) all exhibit significant gender differences. However, the speci...