Study on the Differences in Cortical Layers During Epileptic Seizure Onset and Spread Epilepsy is a neurological disorder that severely impacts patients’ quality of life, affecting approximately 1% of the global population. Among all epilepsy patients, nearly one-third are resistant to pharmaceutical treatments, known as drug-resistant epilepsy. Fo...

Topographical Map of the 1/f Index in the Whole Brain for Parkinson’s Disease Authors: Pascal Helson, Daniel Lundqvist, Per Svenningsson, Mikkel C. Vinding, Arvind Kumar Research Background Parkinson’s Disease (PD) is a progressive and debilitating brain disorder primarily characterized by motor dysfunction but also affecting perceptual and cogniti...

The Effect of Single-Night Continuous Positive Airway Pressure on Spontaneous Brain Activity in Patients with Severe Obstructive Sleep Apnea Research Background Obstructive sleep apnea (OSA) is a common chronic sleep-related breathing disorder characterized by partial or complete closure of the airway during sleep. This condition leads to repeated ...

Consensus Study Report on Pediatric Epilepsy Surgery Background Introduction The incidence of epilepsy varies significantly across different age groups. According to the International League Against Epilepsy (ILAE), the highest incidence rates of epilepsy are found among those under 5 years old and over 65 years old (>60 per 100,000 people), with c...

Alzheimer’s Disease Research and Treatment Frontiers: Beta/Theta Power Ratio in EEG Periodic Components as a Potential Biomarker Background Introduction Alzheimer’s dementia (AD) is a progressively developing disease, accounting for 60% to 80% of all dementia cases [1]. In the early stages of AD, mild cognitive impairment (MCI) typically occurs, du...

Clinical Utility of Non-invasive Imaging in MRI-negative Focal Epilepsy Academic Background Epilepsy surgery is a crucial treatment modality for drug-resistant epilepsy. However, the likelihood of achieving good outcomes postoperatively is significantly diminished when Magnetic Resonance Imaging (MRI) fails to detect lesions. Previous studies indic...

Modulation of P3m Amplitude by Task Difficulty in a Visual Oddball Task Background In cognitive neuroscience research, Event-Related Potentials (ERP) and Event-Related Fields (ERF) are important means to explore the cognitive processing mechanisms of the brain. Among these, the P3 component (referred to as P3m in magnetoencephalography) has garnere...

Deep-learning-based Motor Imagery EEG Classification by Exploiting the Functional Connectivity of Cortical Source Imaging Research Background and Motivation A brain-computer interface (BCI) is a system that directly decodes and outputs brain activity information without relying on related neural pathways and muscles, thereby achieving communication...

Research Background and Objectives With the continuous development of neuroscience, identifying indirectly observed processes related to functional networks has become an important research direction. Researchers attempt to estimate the activity of these functional networks through electrophysiological signals such as EEG and MEG. However, this pro...

Study on the Relationship between Macroscopic Intrinsic Dynamics and Microcircuit Functions in Epilepsy Research Background Epilepsy is a group of neurological disorders characterized by abnormal spontaneous brain activity, involving multi-scale changes in brain functional organization. However, it remains unclear to what extent epilepsy-related sp...