Electrophysiological Signatures of Veridical Head Direction in Humans Navigation is one of the core components of human complex cognition, where head direction information is crucial for positioning oneself in space. However, due to the requirement of having the head fixed in a specific position during most neuroimaging experiments, understanding h...

Brain Mechanism Study on Emotion Processing Bias in Patients with Highly Treatment-Resistant Depression Background Introduction Depression is one of the mental diseases prevalent in modern society that severely affect individuals’ physical and mental health. According to Beck’s cognitive model, the development and maintenance of depression are larg...

Research Background and Objectives Empathy is the ability to understand and share the feelings of others and is a crucial foundation for human social interaction and prosocial behavior. Current neuroimaging studies have identified specific brain regions that play key roles in empathetic pain, including the anterior insula (AI), anterior cingulate c...

Study on the Differences in Cortical Layers During Epileptic Seizure Onset and Spread Epilepsy is a neurological disorder that severely impacts patients’ quality of life, affecting approximately 1% of the global population. Among all epilepsy patients, nearly one-third are resistant to pharmaceutical treatments, known as drug-resistant epilepsy. Fo...

Topographical Map of the 1/f Index in the Whole Brain for Parkinson’s Disease Authors: Pascal Helson, Daniel Lundqvist, Per Svenningsson, Mikkel C. Vinding, Arvind Kumar Research Background Parkinson’s Disease (PD) is a progressive and debilitating brain disorder primarily characterized by motor dysfunction but also affecting perceptual and cogniti...

The Effect of Single-Night Continuous Positive Airway Pressure on Spontaneous Brain Activity in Patients with Severe Obstructive Sleep Apnea Research Background Obstructive sleep apnea (OSA) is a common chronic sleep-related breathing disorder characterized by partial or complete closure of the airway during sleep. This condition leads to repeated ...

Consensus Study Report on Pediatric Epilepsy Surgery Background Introduction The incidence of epilepsy varies significantly across different age groups. According to the International League Against Epilepsy (ILAE), the highest incidence rates of epilepsy are found among those under 5 years old and over 65 years old (>60 per 100,000 people), with c...

Alzheimer’s Disease Research and Treatment Frontiers: Beta/Theta Power Ratio in EEG Periodic Components as a Potential Biomarker Background Introduction Alzheimer’s dementia (AD) is a progressively developing disease, accounting for 60% to 80% of all dementia cases [1]. In the early stages of AD, mild cognitive impairment (MCI) typically occurs, du...

Clinical Utility of Non-invasive Imaging in MRI-negative Focal Epilepsy Academic Background Epilepsy surgery is a crucial treatment modality for drug-resistant epilepsy. However, the likelihood of achieving good outcomes postoperatively is significantly diminished when Magnetic Resonance Imaging (MRI) fails to detect lesions. Previous studies indic...

Modulation of P3m Amplitude by Task Difficulty in a Visual Oddball Task Background In cognitive neuroscience research, Event-Related Potentials (ERP) and Event-Related Fields (ERF) are important means to explore the cognitive processing mechanisms of the brain. Among these, the P3 component (referred to as P3m in magnetoencephalography) has garnere...