Image Classification Based on Bayesian Tensor Modeling for Alzheimer’s Disease Introduction Neuroimaging research is a crucial component of contemporary neuroscience, significantly enhancing our understanding of brain structure and function. Through these non-invasive visualization techniques, researchers can more accurately predict the risk of cer...

Identifying Diagnostic Biomarkers for Autism Spectrum Disorder using the PED Algorithm In the field of neuroinformatics, research on Autism Spectrum Disorder (ASD) predominantly focuses on the bidirectional connectivity between brain regions, with fewer studies addressing higher-order interaction anomalies among brain regions. To explore the comple...

Using fMRI to Guide TMS Target Selection: Reliability and Sensitivity of 3T and 1.5T fMRI Metrics [DOI: 10.1007/s12021-024-09667-5], published in Neuroinformatics Background Introduction The early application of functional magnetic resonance imaging (fMRI) mainly focused on inferring cognitive processes. However, modern medicine is gradually extend...

Research Report on the Enhanced Spatial Fuzzy C-Means Algorithm for Brain Tissue Segmentation Academic Background Magnetic Resonance Imaging (MRI) plays a vital role in neurology, particularly in the precise segmentation of brain tissue. Accurate tissue segmentation is crucial for diagnosing brain injuries and neurodegenerative diseases. Segmenting...

Multi-Year, Multi-Disciplinary Efforts in Scientific Research Data Management Education Research Background With the development of modern neuroscience, Research Data Management (RDM) has become an indispensable skill for scientists. However, despite the importance of research data management for scientific research, such technical skills are often...

MRIO: A Magnetic Resonance Imaging Acquisition and Analysis Ontology Magnetic Resonance Imaging (MRI) is a biomedical imaging technology used to non-invasively visualize internal structures of tissues in three-dimensional space. MRI is widely used in studying the structure and function of the human brain and is a powerful tool for diagnosing neurol...

ADAM10-Mediated Human Prion Protein Cleavage and Its Relationship with Neurodegenerative Diseases Background The endopeptidic processing of multifunctional proteins is crucial for regulating their physiological functions and plays a significant role in various pathological conditions. Prion protein (PrP), a widely expressed glycosylphosphatidylinos...

Research Report on Abnormal Tau Proteins in the Retina of Alzheimer’s Disease Patients Introduction Alzheimer’s disease (AD) is the primary cause of dementia in the elderly population worldwide. The pathological features of AD include the deposition of amyloid beta-protein (Aβ) and the aggregation of abnormal microtubule-associated tau proteins in ...

Cross-Comparative Study of DNA Methylation Patterns in the Frontal Lobe White Matter of Multiple System Atrophy, Parkinson’s Disease, and Progressive Supranuclear Palsy Academic Background Multiple System Atrophy (MSA) is a rare neurodegenerative disease characterized by neuronal loss and gliosis, accompanied by glial cytoplasmic inclusions (GCIs) ...

Characteristics of Premature Cellular Senescence in Alzheimer’s Disease: Application of Single-Nucleus Transcriptomics Research Background and Objectives Alzheimer’s disease (AD) is the most common type of dementia in the elderly, characterized by extracellular deposition of β-amyloid protein and intracellular neurofibrillary tangles. Other patholo...