Hyperspectral In-Memory Computing with Optical Frequency Combs and Programmable Optical Memories

Hyperspectral In-Memory Computing and Applications of Optical Frequency Comb and Programmable Optical Memory Introduction In recent years, breakthroughs in machine learning have driven revolutionary developments in various industries, including healthcare, finance, retail, automotive, and manufacturing. These transformations have led to a surge in ...

Mode-locked Waveguide Polariton Laser

Research Report on the Realization of Blue-Ultraviolet Light Mode-Locking by Polariton Waveguides In the field of modern optoelectronics, continuous advancements in laser technology have greatly propelled the development of information technology, biomedicine, and industrial processing, among other sectors. Mode-locked laser technology, in particul...

On-Demand Orbital Angular Momentum Comb from a Digital Laser

Requirement for Orbital Angular Momentum Comb Modes in Digital Lasers Research Background and Significance With the rapid advancement of information technology, the demand for high-capacity data transmission has become increasingly stringent. Orbital angular momentum (OAM) of light, due to its inherently infinite dimensions, is considered a potenti...

Electrically Engineering Synthetic Magnetic Fields for Polarized Photons

Research Report: Electrically Controlled Engineering of Synthetic Magnetic Fields in Polarized Photons Academic Background and Research Purpose In recent years, synthetic gauge theory has shown its potential in controlling the propagation of light and its state evolution in non-magnetic photonic systems. However, the synthetic magnetic fields gener...

Spin–Orbit Optical Broadband Achromatic Spatial Differentiation Imaging

Spin–Orbit Optical Broadband Achromatic Spatial Differentiation Imaging

Broadband Achromatic Spatial Differential Imaging with Optical Spin-Orbit Coupling Background Introduction In image processing, traditional spatial differentiation is typically accomplished through digital electronic computation. However, many big data applications require real-time and high-throughput image processing, which poses a tremendous cha...

Retrospective Study of Claudin 18 Isoform 2 Prevalence and Prognostic Association in Gastric and Gastroesophageal Junction Adenocarcinoma

Research Report on Claudin 18.2 in Gastric Cancer and Gastroesophageal Junction Adenocarcinoma Background Introduction Gastric cancer and gastroesophageal junction (G/GEJ) adenocarcinoma are major global health burdens. It is estimated that in 2020 alone, there were approximately 1.7 million new cases of gastric and esophageal cancers worldwide, wi...

Predictive Impact of Tumor Mutational Burden on Real-World Outcomes of First-Line Immune Checkpoint Inhibition in Metastatic Melanoma

Predictive Impact of Tumor Mutational Burden on Real-World Outcomes of First-Line Immune Checkpoint Inhibition in Metastatic Melanoma

Study on Real-world Outcomes of First-line Immune Checkpoint Inhibitor Therapy in Metastatic Melanoma Predicted by Tumor Mutational Burden The treatment of metastatic melanoma has significantly benefited from immune checkpoint inhibitors (ICIs) in recent years. However, despite the remarkable improvement in survival rates among melanoma patients, t...

Regorafenib in Patients with Solid Tumors: Results from the TAPUR Study

The Use of Regorafenib in Patients with BRAF-Mutant Solid Tumors: A Summary of Results from the TAPUR Study Background Introduction The BRAF gene belongs to the cytoplasmic serine/threonine kinase family and regulates cell proliferation and survival by activating the mitogen-activated protein kinase signaling pathway (MAPK). BRAF mutations can lead...

Tumor Size Is Not Everything: Advancing Radiomics as a Precision Medicine Biomarker in Oncology Drug Development and Clinical Care

In contemporary clinical oncology practice and drug development, the methods for evaluating tumor response are on the cusp of a revolution. Since the World Health Organization (WHO) proposed tumor response classification criteria for assessing the effectiveness of anti-cancer drugs in 1981, this field has undergone several improvements. Notably, th...

Transcriptomic Profiling of Primary Prostate Cancers and Nonlocalized Disease on Prostate-Specific Membrane Antigen PET/CT: A Multicenter Retrospective Study

Transcriptomic Analysis of Prostate Cancer Patients: A Study on Nonlocalized Disease Based on Prostate-Specific Membrane Antigen Positron Emission Tomography/Computed Tomography Academic Background Prostate cancer is a common male malignancy, and its diagnosis and treatment are crucial to patient prognosis. Transcriptomic analysis is a technique us...