Safety and Efficacy of Surgical Implantation of Intrathecal Drug Delivery Pumps in Patients With Cancer With Refractory Pain

Safety and Efficacy of Intrathecal Drug Delivery Pumps for Intractable Pain in Cancer Patients Introduction Pain management in cancer patients is a critical issue in palliative care, as clinicians strive to improve patients’ quality of life and alleviate their suffering. Most cancer patients experience cancer-related pain, and 30%-40% of them suffe...

Extent of Resection Thresholds in Molecular Subgroups of Newly Diagnosed Isocitrate Dehydrogenase–Wildtype Glioblastoma

Extent of Resection Thresholds in Molecular Subgroups of Newly Diagnosed Isocitrate Dehydrogenase–Wildtype Glioblastoma

Study on the Extent of Resection Threshold in Different Molecular Subtypes of Newly Diagnosed IDH-wildtype Glioblastoma Introduction Glioblastoma (GBM) is the most common malignant brain tumor in adults. Although surgical resection, radiotherapy, and chemotherapy are the current standard treatment regimens, the prognosis of GBM remains poor, with a...

Surgical Outcomes of Low-Flow Bypass Surgery in Intracranial Atherosclerotic Steno-Occlusive Diseases

This is a report on a scholarly article regarding the treatment results of low-bypass surgery for 215 patients with intracranial atherosclerotic stenosis or occlusion at Seoul National University Hospital. Background Introduction: Intracranial atherosclerotic disease (ICAD) causing stenosis or occlusion is one of the major causes leading to ischemi...

Scalp nerve block alleviates headaches associated with sonication during transcranial magnetic resonance–guided focused ultrasound

In this academic paper, the authors attempt to address the common headache complication during magnetic resonance-guided focused ultrasound (mrgFUS) treatment. Headache is a common complication, and in severe cases, it may even cause patients to be unable to tolerate ultrasound radiation and terminate the treatment. There is currently no establishe...

55-year follow-up of the first adult patient with craniopharyngioma treated with gamma knife radiosurgery

This is a report on the 55-year follow-up of the first case of a craniopharyngioma patient who underwent gamma knife radiosurgery. The article details the medical history, diagnosis process, gamma knife surgery details, as well as the 55-year follow-up with multiple treatments, providing a comprehensive overview of the patient’s long medical journe...

Effective and Successful Control of Symptomatic Vertebral Hemangiomas with Epidural Extension Using Stereotactic Spine Radiosurgery

Vertebral hemangiomas are the most common primary tumors of the spine. Most vertebral hemangiomas are asymptomatic benign lesions, but in a few cases, if the mass grows and extends into the epidural space, compressing the spinal cord or nerve roots, it may lead to neurological symptoms such as pain, sensory abnormalities, or motor deficits. The tre...

Outcomes of Mechanical Thrombectomy for Patients with Stroke Presenting with Low Alberta Stroke Program Early Computed Tomography Score in Early and Late Time Windows

Outcomes of Mechanical Thrombectomy for Stroke Patients with Low Alberta Stroke Program Early CT Score Background Acute ischemic stroke is a life-threatening disease, and large vessel occlusion is one of the major causes of severe disability. Mechanical thrombectomy (MT) has become the standard treatment for acute ischemic stroke, with multiple cli...

Patterns of Sagittal Imbalance in Degenerative Kyphosis and Its Implication on Postoperative Mechanical Failure

Patterns of Sagittal Imbalance in Degenerative Kyphosis and Its Implication on Postoperative Mechanical Failure

Sagittal Imbalance Patterns in Degenerative Kyphosis of the Lumbar or Thoracolumbar Spine and Their Impact on Postoperative Complications Research Background Degenerative kyphosis (DK) is the most common type of spinal deformity in the elderly. Sagittal imbalance is a typical radiological feature of DK and is associated with a severe decline in qua...

Caudal Agenesis: Classification Based on the Pathoembryogenesis of the Spinal Cord

This is a report on a new classification method for caudal agenesis: Caudal agenesis is a congenital disorder characterized by the absence of lower vertebrae. Previous classifications of caudal agenesis were primarily based on the level of bony deficiency or the position of the terminal spinal cord, but there has been debate as to whether these cla...

The Association Between Task Complexity and Cortical Language Mapping Accuracy

Correlation between Task Complexity and Accuracy of Cortical Language Mapping Introduction This study aimed to investigate whether task complexity affects the accuracy of mapping language functions during direct cortical stimulation mapping (DCS). The researchers hypothesized that due to the reduced computational ability of neurons in the cortex in...