Oscillatory Contractile Forces Refine Endothelial Cell-Cell Interactions for Continuous Lumen Formation Governed by Heg1/CCM1

Academic Background The formation and maintenance of vascular networks are critical processes in embryonic development and tissue regeneration, involving the regulation of various biophysical forces. Endothelial cells (ECs) play a central role in angiogenesis and vasculogenesis, with the contractile forces of the cytoskeleton (actomyosin contractil...

Global Surveillance of Circulating MicroRNA for Diagnostic and Prognostic Assessment of Acute Myocardial Infarction Based on Plasma Small RNA Sequencing

Global Surveillance of Circulating MicroRNA for Diagnostic and Prognostic Assessment of Acute Myocardial Infarction Based on Plasma Small RNA Sequencing Academic Background Acute Myocardial Infarction (AMI) is one of the most severe cardiovascular diseases leading to human mortality and morbidity worldwide. The pathological mechanism of AMI primari...

Cardiac Dysfunction Among Breast Cancer Survivors: Role of Cardiotoxic Therapy and Cardiovascular Risk Factors

Report on the Study of Cardiac Dysfunction Among Breast Cancer Survivors Academic Background Breast cancer is the most common cancer diagnosed in women. Advances in early detection and novel therapeutics have yielded 5-year survival rates exceeding 90%. However, with over four million breast cancer survivors in the United States today, the quality ...

Effectiveness of a Cardiovascular Health Electronic Health Record Application for Cancer Survivors in Community Oncology Practice

Effectiveness of a Cardiovascular Health Electronic Health Record Application for Cancer Survivors in Community Oncology Practice Academic Background The cardiovascular health (CVH) of cancer survivors has become an increasingly important concern. Studies have shown that cancer survivors generally have poorer cardiovascular health, partly due to th...

Diagnostic Accuracy of Dynamic Stress Myocardial CT Perfusion in Patients with Stents: The ADVANTAGE 2 Study

Diagnostic Accuracy of Dynamic CT Perfusion in Patients with Coronary Stents Academic Background Coronary artery disease (CAD) is one of the leading causes of death worldwide. Percutaneous coronary intervention (PCI) is a common treatment for obstructive CAD. However, after stent implantation, patients may experience in-stent restenosis (ISR) or pr...

Prognostic Value of Coronary CT Angiography–Derived Quantitative Flow Ratio in Suspected Coronary Artery Disease

Prognostic Value of Coronary CT Angiography-Derived Quantitative Flow Ratio in Suspected Coronary Artery Disease Academic Background Coronary artery disease (CAD) is one of the leading causes of death and disability worldwide. Coronary CT angiography (CTA) is recommended as a first-line noninvasive test for patients with suspected or known CAD. CTA...

CT-Guided Left Stellate Ganglion Cryoneurolysis for Refractory Ventricular Arrhythmias

Report on CT-Guided Left Stellate Ganglion Cryoneurolysis for Refractory Ventricular Arrhythmias Academic Background Ventricular arrhythmias (VAs), including ventricular tachycardia and ventricular fibrillation, pose a significant challenge in cardiovascular medicine due to their high morbidity, mortality, and increasing prevalence. Although curren...

Myocardial Fibrosis Assessment at 3-T versus 5-T Myocardial Late Gadolinium Enhancement MRI: Early Results

Feasibility of Myocardial Late Gadolinium Enhancement MRI at 5T versus 3T for Myocardial Fibrosis Assessment Academic Background Myocardial fibrosis is a common pathological feature of various cardiac diseases, and accurate assessment of myocardial fibrosis is crucial for diagnosis, treatment, and prognosis. Cardiac magnetic resonance imaging (MRI)...

A Potential Coagulation-Related Diagnostic Model Associated with Immune Infiltration for Acute Myocardial Infarction

Potential Coagulation-Related Diagnostic Model Associated with Immune Infiltration for Acute Myocardial Infarction Academic Background Acute Myocardial Infarction (AMI) is one of the leading causes of death worldwide. Despite significant advancements in diagnosis, treatment, and prognosis in recent years, the incidence and mortality rates of AMI re...

Foundation Model of ECG Diagnosis: Diagnostics and Explanations

Research on ECG Diagnosis Foundation Model Based on Signal-Language Architecture Academic Background Cardiovascular disease (CVD) is the leading cause of death worldwide, and early identification of high-risk populations is crucial. The electrocardiogram (ECG), a non-invasive, cost-effective, and widely used diagnostic tool, is recorded over 300 mi...