Electroencephalography-Guided Anesthesia and Delirium in Older Adults after Cardiac Surgery

EEG-Guided Anesthesia and Delirium in Elderly Patients After Cardiac Surgery Research Background Delirium is a common postoperative complication in elderly patients, particularly after cardiac surgery. Delirium not only leads to cognitive decline but also increases hospitalization time and medical costs. Current preventive measures are limited in e...

Associations of Internal Medicine Residency Milestone Ratings and Certification Examination Scores with Patient Outcomes

Associations of Internal Medicine Residency Milestone Ratings and Certification Examination Scores with Patient Outcomes

Association Between Milestone Ratings and Certification Exam Scores of Medical Residents and Patient Outcomes Background In the United States, the education and competency assessment of internal medicine residents are primarily conducted through two methods: the Milestone assessment system and the American Board of Internal Medicine (ABIM) certific...

Physical Exercise Inhibits Cognitive Impairment and Memory Loss in Aged Mice, and Enhances Pre- and Post-Synaptic Proteins in the Hippocampus of Young and Aged Mice

A scientific paper authored by Ricardo Augusto Leoni de Sousa and his research team was published in Volume 26, Issue 31 of the journal “Neuromolecular Medicine” in 2024. The paper is titled “Physical exercise inhibits cognitive impairment and memory loss in aged mice, and enhances pre- and post-synaptic proteins in the hippocampus of young and age...

Effects of Chronic Hypertension on the Energy Metabolism of Cerebral Cortex Mitochondria in Normotensive and Spontaneously Hypertensive Rats During Aging

Effects of Chronic Hypertension on Mitochondrial Energy Metabolism in the Cerebral Cortex of Normal and Spontaneously Hypertensive Rats Background Introduction Chronic hypertension has destructive structural and functional consequences for cerebral vessels and brain parenchyma. Hypertension impairs cerebrovascular autoregulation (Ferrari & Villa, 2...

Lycium Barbarum Polysaccharides Improves Cognitive Functions in ICV-STZ-Induced Alzheimer’s Disease Mice Model by Improving the Synaptic Structural Plasticity and Regulating IRS1/PI3K/AKT Signaling Pathway

Study on the Improvement of Cognitive Function in ICV-STZ-Induced Alzheimer’s Disease Mouse Model by Lycium Barbarum Polysaccharides Research Background Alzheimer’s disease (AD) is the most common neurodegenerative disease of the central nervous system, characterized by progressive cognitive impairment, memory loss, personality changes, and emotion...

Compensation or Preservation? Different Roles of Functional Lateralization in Speech Perception of Older Non-Musicians and Musicians

The Impact of Music Training on Language Perception in Older Adults Under Global Aging Challenges Research Background As global population aging accelerates, the decline in language perception ability of older adults in noisy environments has become a notable issue. Older adults, even with normal hearing, often encounter the “cocktail party problem...

Alleviating CB2-dependent ER stress and mitochondrial dysfunction improves chronic cerebral hypoperfusion-induced cognitive impairment

Research Overview and Background With the acceleration of global aging, the incidence of ischemic cerebrovascular diseases is also rising significantly. Elderly people over 65 are particularly susceptible to cognitive decline caused by cerebral ischemia, making Chronic Cerebral Hypoperfusion (CCH) a major cause of cognitive impairment and Vascular ...

Perioperative levels of IL8 and IL18, but not IL6, are associated with nucleus basalis magnocellularis atrophy three months after surgery

Association Study of Perioperative IL8 and IL18 Levels with Brain Basal Ganglia Atrophy Three Months After Surgery Background In recent years, an increasing number of studies have shown that surgical procedures may accelerate brain atrophy. Meanwhile, the relationship between systemic inflammation and neurodegenerative diseases has also received co...

Longitudinal Associations Between Time Perspective and Life Satisfaction Across Adulthood

Research Report on the Long-term Relationship between Time Perspective and Life Satisfaction in Adulthood Research Background Time perspective is an important predictor of human well-being. However, time perspective itself changes with development. A future-dominated time perspective gradually gives way to a present and past-focused perspective as ...

Trend Change Analysis of Postural Balance in Parkinson’s Disease Discriminates Between Medication State

Analysis of Trend Changes in Static Balance of Parkinson’s Disease Patients to Distinguish Drug States Introduction Maintaining static body balance is crucial for daily living, which requires coordination between different body segments. Any change or decline in balance ability increases the risk of falling. Patients with Parkinson’s disease (PD) e...