Association between Time to Treatment with Endovascular Thrombectomy and Home-Time after Acute Ischemic Stroke

The Relationship between Treatment Speed of Endovascular Thrombectomy (EVT) for Acute Ischemic Stroke and Patient’s “Time at Home” Stroke is an acute disease with high disability and mortality rates. However, in recent years, the treatment efficacy of acute ischemic stroke has improved significantly with the development of endovascular thrombectomy...

Analysis of Cerebral CT Based on Supervised Machine Learning as a Predictor of Outcome After Out-of-Hospital Cardiac Arrest

Brain CT Analysis as a Tool for Outcome Prediction after Out-of-Hospital Cardiac Arrest: A Supervised Machine Learning Analysis Research Background Out-of-Hospital Cardiac Arrest (OHCA) is one of the leading causes of death in the Western world, with extremely low survival rates, ranging from 3% to 16%. The neurological and overall outcomes after O...

Contemporary Cohort of Cerebral Cavernous Malformations: Natural History and Utility of Follow-Up MRI

Natural History and MRI Follow-up of Patients with Cerebral Cavernous Malformations Background Cerebral cavernous malformations (CCMs) are vascular malformations of the brain and spinal cord lined by endothelial cells and lacking smooth muscle. Due to the disruption of endothelial cell permeability and tight junctions, patients may present with foc...

Associations of Epigenetic Age Estimators with Cognitive Function Trajectories in the Women's Health Initiative Memory Study

Association Between Epigenetic Age Acceleration Estimates and Cognitive Trajectories in the Women’s Health Initiative Memory Study Background Maintaining cognitive function is crucial for independent living among older adults. With the growth of the aging population, cognitive decline has become a significant public health challenge. Many studies h...

Phantom and In Vivo Accuracy of Frameless Optical Navigation in Stereotactic Laser Interstitial Thermal Therapy

Accuracy of Frameless Optical Navigation in Stereotactic Laser Interstitial Thermal Therapy Background Glioblastoma is a rapidly growing and invasive brain tumor, and traditional treatment methods include surgical resection, radiation therapy, and chemotherapy. However, for some patients with deep-seated tumors or poor physical conditions, traditio...

Method for Localizing the Seizure Onset Zone in Refractory Epilepsy Patients

In recent years, refractory epilepsy has received increasing attention from the medical community. Refractory epilepsy is defined as the continuing occurrence of severe seizures despite treatment with two appropriate antiepileptic drugs. For patients who are unresponsive to drug treatment, if the seizure onset zone (SOZ) can be accurately localized...

Laser Interstitial Thermal Therapy for First-Line Treatment of Insular Glioma: A Novel Treatment Framework

Application of Laser Interstitial Thermal Therapy in Insular Gliomas Research Background and Problem Statement The management of insular gliomas has always faced significant surgical challenges. Due to the complex functional and vascular anatomy surrounding the insula, maximally safe resection is highly technically challenging. Removing low-grade a...

Outcomes of Mechanical Thrombectomy for Acute Ischemic Stroke in Cancer Patients: A Single-Center Experience and Meta-Analysis

Research Report: Mechanical Thrombectomy Outcomes in Acute Ischemic Stroke Patients with Cancer Background Acute ischemic stroke (AIS) caused by large vessel occlusion (LVO) is a severe neurological injury, which is further complicated in cancer patients. Cancer-related stroke mechanisms include a hypercoagulable state, coagulopathies due to tumor-...

An Anatomo-Functional Study of the Interactivity Between the Paracentral Lobule and the Primary Motor Cortex

Neurosurgical Research: Anatomical and Functional Study of Connections between the Paracentral Lobule and Primary Motor Cortex In recent years, researchers have been continuously exploring the connections between different regions of the human brain, particularly those involving motor function and its plasticity. It is known that the paracentral lo...

Laser Interstitial Thermal Therapy in Neurosurgery: A Single-Surgeon Experience of 313 Patients

Laser Interstitial Thermal Therapy in Neurosurgery: A Single-Surgeon Experience of 313 Patients

Clinical Study Report on Laser Interstitial Thermal Therapy (LITT) in Neurosurgery Background Introduction With the continuous progress of modern medical technology, Laser Interstitial Thermal Therapy (LITT) has gradually gained a foothold in the field of neurosurgical tumor treatment, especially in treating intracranial lesions that are difficult ...