ABHD6 Drives Endocytosis of AMPA Receptors to Regulate Synaptic Plasticity and Learning Flexibility Research Background In the exploration of the neural system’s mechanisms, α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors (AMPAR) maintain the tuning ability of neurons in both resting and active states through the regulation of...

Study Reveals Molecular Mechanisms of Enhanced Cocaine Craving in Rats During Withdrawal Background Introduction The issue of relapse in drug abuse poses a significant challenge in addiction treatment. According to related research, relapse behaviors in drug addiction are often triggered by environmental cues associated with drug use. This phenomen...

Academic Report on “Contralateral Delay Activity and Alpha Lateralization Reflect Retinotopic and Screen-Centered Reference Frames in Visual Memory” Introduction The visual system is organized in a lateralized manner, with the left and right visual fields processed by the contralateral cerebral cortex. This organization applies not only to percepti...

New Findings in Alzheimer’s Disease Research: The Regulatory Role of Signal Peptide Peptidase-Like 2b in the β-Amyloid Cascade Alzheimer’s Disease (AD) is a complex neurodegenerative disorder characterized by the abnormal accumulation of β-amyloid peptides (Aβ) in brain tissue and the formation of intracellular neurofibrillary tangles. The abnormal...

Analyzing the Gene Expression Network in Developing Hippocampus from the Perspective of NEIL3 Deficiency Background The hippocampus, a crucial region of the brain, is well-regarded for its key roles in memory consolidation, information processing, and emotional regulation. In the field of neuroscience research, the gene regulatory mechanisms of the...

The Regulatory Mechanism of Central Complement C3a Receptor on LPS-Induced Depressive-Like Behavior Introduction With the increasing number of depression patients globally, major depressive disorder (MDD) has become one of the leading causes of disability worldwide. The symptoms, treatment effects, and biological correlations of depression exhibit ...

Epilepsy is one of the most common neurological disorders, with temporal lobe epilepsy (TLE) being the most prevalent form of drug-resistant epilepsy in adults. Numerous studies have indicated that TLE involves not only pathological changes in the medial temporal lobe but also affects widespread brain structures and functions. In this scientific re...

New Discoveries in Brain Science: The Relationship Between Early Lateralization of Dorsal White Matter Tracts Targeting Broca’s Area and Language Development Research Background Language development is one of the key areas in human cognitive science. Existing research indicates that language functions in the adult brain exhibit significant laterali...

Analysis of the Effect of Central LEAP-2 on Food Intake and Its Impact on Nucleus Accumbens Dopamine Release Background Introduction Gut-brain peptides such as ghrelin and their receptors have been established as important factors in regulating hunger and reward processing. However, the liver-expressed antimicrobial peptide 2 (Leap2), an inverse ag...

This academic paper, authored by researchers Elizabeth C. Heaton, Esther H. Seo, Laura M. Butkovich, Sophie T. Yount, and Shannon L. Gourley, primarily explores the role of the melanocortin system in the dorsal striatum in controlling goal-directed behavior and inflexible behavior, particularly in inhibiting habitual behavior in the dorsolateral st...