Magnetoencephalography-Derived Oscillatory Microstate Patterns Across Lifespan: The Cambridge Centre for Ageing and Neuroscience Cohort

Application of Magnetoencephalography (MEG) to Analyze Changes in Whole-Brain Oscillatory Microstate Patterns Across the Lifespan: Cambridge Centre for Aging and Neuroscience Cohort Study Research Background With the increasing seriousness of the aging population problem, understanding the neurophysiological changes during the aging process becomes...

The Cortical Neurophysiological Signature of Amyotrophic Lateral Sclerosis

Analysis of Cortical Neurophysiological Characteristics of ALS and Its Potential as a Biomarker Background Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disease that affects adults, characterized by a gradual loss of the integrity of the brain, spinal cord, and peripheral motor system. Although clinical and genetic studies have reveale...

Negation Mitigates Rather Than Inverts the Neural Representations of Adjectives

Background Introduction A notable characteristic of human language processing is our ability to combine stored lexical elements, i.e., words, as needed to flexibly generate or alter current meanings. At the core of this process is how we construct semantic representations in real time. Although research on the generation of syntactic structures has...

Phase-dependent word perception emerges from region-specific sensitivity to the statistics of language

Phase-dependent word perception emerges from region-specific sensitivity to the statistics of language

Phase-Dependent Language Perception in Neural Oscillations: An Interdisciplinary Study Report Background During speech perception, the phase of neural oscillations plays a crucial role in the separation of neural representations and perceptual decisions. However, the specific phase-encoding mechanisms remain unclear. This study aims to reveal how p...

Neural Representations of Perspectival Shapes and Attentional Effects: Evidence from fMRI and MEG

Neural Representation of Perspective Shapes and the Effect of Attention: Evidence from fMRI and MEG Introduction We always perceive objects from a specific perspective. In many cases, the shape we rely on when observing an object, the perspective shape, differs from its objective shape, the physical shape in the real world. For instance, a coin rot...

Reactivation strength during cued recall is modulated by graph distance within cognitive maps

Reactivation Strength in Memory is Modulated by Graph Distance in Cognitive Maps Research Background Memory formation and retrieval are among the crucial areas of research in neuroscience. Classic memory theories propose that memory depends on three distinct stages: encoding, consolidation, and retrieval. New episodic memories are formed through en...

Tracking the Neurodevelopmental Trajectory of Beta Band Oscillations with Optically Pumped Magnetometer-based Magnetoencephalography

Tracking the Neurodevelopmental Trajectory of Beta Band Oscillations with Optically Pumped Magnetometer-based Magnetoencephalography

Research Background Neural oscillations are fundamental components of brain function, coordinating electrophysiological activities within and between neural assemblies, which is crucial for cognitive and behavioral processes. During children’s growth, the development of these neural processes is not only an important neuroscience issue but also can...

Somatosensory Evoked Spikes in Normal Adults Detected by Magnetoencephalography

Somatosensory Evoked Spikes in Normal Adults Detected by Magnetoencephalography Research Background and Motivation Since 1949, clinical neurophysiology research has discovered that high-voltage cortical somatosensory evoked potentials (SEPs) can be detected in patients with reflex epilepsy, where seizures are triggered by somatosensory stimulation ...

Spatiotemporal Brain Hierarchies of Auditory Memory Recognition and Predictive Coding

Spatiotemporal Brain Hierarchies of Auditory Memory Recognition and Predictive Coding

The Spatiotemporal Hierarchical Structure of the Brain in Auditory Memory Recognition and Predictive Coding Background This study aims to explore the hierarchical brain mechanisms involved in human identification of previously memorized music sequences and their systematic changes. While extensive research has been conducted on neural processing of...

Post-Task Responses Following Working Memory and Movement Are Driven by Transient Spectral Bursts with Similar Characteristics

Background and Research Questions Working memory and post-task responses (PTRs) in the brain have been a focal point in neuroscience research. Previous studies have shown that post-movement beta rebound (PMBR) is a reliable and stable phenomenon in the cerebral cortex that can be studied and measured using magnetoencephalography (MEG). Recent resea...