Gamma Oscillations of Visual Cortex Underlying Emotion and Cognition Deficits Associated with Suicide Attempt in Major Depressive Disorder

Research on Gamma Oscillations Related to Suicidal Behavior in Patients with Depression Introduction Suicide is one of the most severe human behaviors globally, particularly prevalent among patients with Major Depressive Disorder (MDD). Studies have shown that nearly half of those who die by suicide had been diagnosed with MDD. Despite its signific...

Intracranial EEG signals disentangle multi-areal neural dynamics of vicarious pain perception

Intracranial EEG signals disentangle multi-areal neural dynamics of vicarious pain perception

Research Background and Objectives Empathy is the ability to understand and share the feelings of others and is a crucial foundation for human social interaction and prosocial behavior. Current neuroimaging studies have identified specific brain regions that play key roles in empathetic pain, including the anterior insula (AI), anterior cingulate c...

A Spatial Perturbation Framework to Validate Implantation of the Epileptogenic Zone

Evaluation of Epilepsy Seizure Onset Zone (SOZ) Implantation Quality through Spatial Perturbation Framework in Pre-Surgical Planning Background The success of epilepsy surgery relies heavily on the accuracy of pre-surgical planning, which typically involves identifying the epileptic zone (EZ) using clinical symptomatology, electroencephalography (E...

Age-Related Changes in the Susceptibility to Visual Illusions of Size

As the global population ages, understanding the impact of aging on visual perception becomes increasingly important. This study investigates age-related changes in size perception in adults through three visual illusions: the Ponzo illusion, the Ebbinghaus illusion, and the height-width illusion. Based on a Bayesian model that conceptualizes the a...

Differential Cortical Layer Engagement During Seizure Initiation and Spread in Humans

Differential Cortical Layer Engagement During Seizure Initiation and Spread in Humans

Study on the Differences in Cortical Layers During Epileptic Seizure Onset and Spread Epilepsy is a neurological disorder that severely impacts patients’ quality of life, affecting approximately 1% of the global population. Among all epilepsy patients, nearly one-third are resistant to pharmaceutical treatments, known as drug-resistant epilepsy. Fo...

Cortex-wide Topography of 1/f-exponent in Parkinson’s Disease

Cortex-wide Topography of 1/f-exponent in Parkinson’s Disease

Topographical Map of the 1/f Index in the Whole Brain for Parkinson’s Disease Authors: Pascal Helson, Daniel Lundqvist, Per Svenningsson, Mikkel C. Vinding, Arvind Kumar Research Background Parkinson’s Disease (PD) is a progressive and debilitating brain disorder primarily characterized by motor dysfunction but also affecting perceptual and cogniti...

Effects of a Single Night of Continuous Positive Airway Pressure on Spontaneous Brain Activity in Severe Obstructive Sleep Apnea

The Effect of Single-Night Continuous Positive Airway Pressure on Spontaneous Brain Activity in Patients with Severe Obstructive Sleep Apnea Research Background Obstructive sleep apnea (OSA) is a common chronic sleep-related breathing disorder characterized by partial or complete closure of the airway during sleep. This condition leads to repeated ...

Consensus on Pediatric Epilepsy Surgery for Young Children

Consensus Study Report on Pediatric Epilepsy Surgery Background Introduction The incidence of epilepsy varies significantly across different age groups. According to the International League Against Epilepsy (ILAE), the highest incidence rates of epilepsy are found among those under 5 years old and over 65 years old (>60 per 100,000 people), with c...

Beta to Theta Power Ratio in EEG Periodic Components as a Potential Biomarker in Mild Cognitive Impairment and Alzheimer's Dementia

Alzheimer’s Disease Research and Treatment Frontiers: Beta/Theta Power Ratio in EEG Periodic Components as a Potential Biomarker Background Introduction Alzheimer’s dementia (AD) is a progressively developing disease, accounting for 60% to 80% of all dementia cases [1]. In the early stages of AD, mild cognitive impairment (MCI) typically occurs, du...

Yield of Non-Invasive Imaging in MRI-Negative Focal Epilepsy

Clinical Utility of Non-invasive Imaging in MRI-negative Focal Epilepsy Academic Background Epilepsy surgery is a crucial treatment modality for drug-resistant epilepsy. However, the likelihood of achieving good outcomes postoperatively is significantly diminished when Magnetic Resonance Imaging (MRI) fails to detect lesions. Previous studies indic...