Age-Related Changes in the Susceptibility to Visual Illusions of Size

As the global population ages, understanding the impact of aging on visual perception becomes increasingly important. This study investigates age-related changes in size perception in adults through three visual illusions: the Ponzo illusion, the Ebbinghaus illusion, and the height-width illusion. Based on a Bayesian model that conceptualizes the a...

Differential Cortical Layer Engagement During Seizure Initiation and Spread in Humans

Differential Cortical Layer Engagement During Seizure Initiation and Spread in Humans

Study on the Differences in Cortical Layers During Epileptic Seizure Onset and Spread Epilepsy is a neurological disorder that severely impacts patients’ quality of life, affecting approximately 1% of the global population. Among all epilepsy patients, nearly one-third are resistant to pharmaceutical treatments, known as drug-resistant epilepsy. Fo...

Cortex-wide Topography of 1/f-exponent in Parkinson’s Disease

Cortex-wide Topography of 1/f-exponent in Parkinson’s Disease

Topographical Map of the 1/f Index in the Whole Brain for Parkinson’s Disease Authors: Pascal Helson, Daniel Lundqvist, Per Svenningsson, Mikkel C. Vinding, Arvind Kumar Research Background Parkinson’s Disease (PD) is a progressive and debilitating brain disorder primarily characterized by motor dysfunction but also affecting perceptual and cogniti...

Effects of a Single Night of Continuous Positive Airway Pressure on Spontaneous Brain Activity in Severe Obstructive Sleep Apnea

The Effect of Single-Night Continuous Positive Airway Pressure on Spontaneous Brain Activity in Patients with Severe Obstructive Sleep Apnea Research Background Obstructive sleep apnea (OSA) is a common chronic sleep-related breathing disorder characterized by partial or complete closure of the airway during sleep. This condition leads to repeated ...

Consensus on Pediatric Epilepsy Surgery for Young Children

Consensus Study Report on Pediatric Epilepsy Surgery Background Introduction The incidence of epilepsy varies significantly across different age groups. According to the International League Against Epilepsy (ILAE), the highest incidence rates of epilepsy are found among those under 5 years old and over 65 years old (>60 per 100,000 people), with c...

Beta to Theta Power Ratio in EEG Periodic Components as a Potential Biomarker in Mild Cognitive Impairment and Alzheimer's Dementia

Alzheimer’s Disease Research and Treatment Frontiers: Beta/Theta Power Ratio in EEG Periodic Components as a Potential Biomarker Background Introduction Alzheimer’s dementia (AD) is a progressively developing disease, accounting for 60% to 80% of all dementia cases [1]. In the early stages of AD, mild cognitive impairment (MCI) typically occurs, du...

Yield of Non-Invasive Imaging in MRI-Negative Focal Epilepsy

Clinical Utility of Non-invasive Imaging in MRI-negative Focal Epilepsy Academic Background Epilepsy surgery is a crucial treatment modality for drug-resistant epilepsy. However, the likelihood of achieving good outcomes postoperatively is significantly diminished when Magnetic Resonance Imaging (MRI) fails to detect lesions. Previous studies indic...

Modulating the Difficulty of a Visual Oddball-like Task and P3m Amplitude

Modulation of P3m Amplitude by Task Difficulty in a Visual Oddball Task Background In cognitive neuroscience research, Event-Related Potentials (ERP) and Event-Related Fields (ERF) are important means to explore the cognitive processing mechanisms of the brain. Among these, the P3 component (referred to as P3m in magnetoencephalography) has garnere...

Neurophysiological Study of Orientation Discrimination in a Working Memory Task

Neurophysiological Study: Neurophysiological Research on Orientation Discrimination in a Working Memory Task Background Recognizing and remembering the spatial orientation of the environment is a crucial component of visuospatial behavior. Accurately storing and recalling this information helps us navigate in space and respond adaptively to rapid c...

Theta Oscillations Support Prefrontal-Hippocampal Interactions in Sequential Working Memory

Study on Theta Oscillations in Hippocampus-Prefrontal Interaction Supporting Sequential Working Memory Academic Background The dorsolateral prefrontal cortex (DLPFC) and the hippocampus play crucial roles in sequential working memory, but the specific interaction mechanisms are not yet clear. Previous studies have shown that these two brain regions...