Research Report on Changes in Functional Connectivity in Post-Stroke Epilepsy (PSE) Patients Based on Source-Level EEG and Graph Theory Research Background Epilepsy has various etiologies, including idiopathic, congenital, head trauma, central nervous system infections, brain tumors, neurodegenerative diseases, and cerebrovascular diseases. Among t...

Research on Drug-Disease Association Prediction Using Graph Contrastive Learning Based on Layered Negative Sampling The prediction of drug-disease associations (RDAs) plays a critical role in unveiling disease treatment strategies and promoting drug repurposing. However, existing methods mainly rely on limited domain-specific knowledge when predict...

Research Report on Immunotherapy Efficacy Prediction for Non-Small Cell Lung Cancer: A Study of Multi-View Adaptive Weighted Graph Convolutional Networks Background Introduction Lung cancer is a highly prevalent and poorly prognostic malignant tumor with a persistently high mortality rate. Among all lung cancer patients, Non-Small Cell Lung Cancer ...

Background and Research Motivation It is well-known that food nutrition is closely related to human health. Scientific research has shown that improper dietary nutrition is linked to more than 200 diseases. Especially when considering the metabolic processes of gut microbiota, the complex interactions between food nutrients and diseases become diff...

Predicting Drug-Target Affinity Based on Learning Protein Knowledge from Biological Networks Background The prediction of drug-target affinity (DTA) plays a crucial role in drug discovery. Efficient and accurate DTA prediction can significantly reduce the time and economic costs of new drug development. In recent years, the explosive development of...

Application of Knowledge-Enhanced Graph Topic Transformer in Interpretable Biomedical Text Summarization Research Background Due to the continuous increase in the volume of biomedical literature, the task of automatic biomedical text summarization has become increasingly important. In 2021 alone, 1,767,637 articles were published in the PubMed data...

Multiple Prior Knowledge Graph Neural Network in Multi-Omics Data Analysis Background Introduction Precision medicine is an important field for the future of healthcare as it provides personalized treatment plans for patients, improving treatment outcomes and reducing costs. For instance, due to the complex clinical, pathological, and molecular cha...

Thalamocortical Connectivity Reduction in Rolandic Epilepsy Rolandic Epilepsy (RE), also known as self-limited epilepsy with centrotemporal spikes (SELECTS), is the most common localized developmental epileptic encephalopathy. This type of epilepsy is typically accompanied by transient mild to severe cognitive symptoms, sleep-related rolandic spike...

Study on the Correlation between Adult Auditory Language Comprehension and Resting-State Alpha Wave Power Academic Background and Research Question Although individual differences in adult language processing have been documented in literature, the neural basis largely remains to be explored. Existing research primarily focuses on how general cogni...

The Level of Salivary Testosterone and Pain Perception Show Sex-Specific Associations in Healthy Adults, But Not in Migraine Patients Introduction Understanding the complexity of pain and the role gender plays in pain perception is of significant importance in medical research. Pain is an unpleasant sensory and emotional experience associated with ...