Academic Background Three-dimensional (3D) high-resolution large-volume imaging has remained a significant challenge in the field of biomedical research. Traditional two-dimensional (2D) slice imaging, while capable of providing planar morphological information of tissues and cells, fails to comprehensively display internal 3D structural informatio...
Impact of Dietary Zinc on Stimulated Zinc Secretion MRI in the Healthy and Malignant Mouse Prostate Academic Background Zinc (Zn²⁺) is an essential trace element in biological systems, participating in various physiological processes, including enzyme catalysis, structural regulation of transcription factors, immune system modulation, and cell prol...
Uranium-Free KMnO₄/Pb Staining Enables Imaging of Tissue Architectures in Low Vacuum Scanning Electron Microscopy Academic Background Electron Microscopy (EM) is one of the most powerful tools for studying the ultrastructure of cells and tissues. However, traditional metal staining methods for biological samples often require the use of harmful ura...
Nucleosome Fibre Topology Guides Transcription Factor Binding to Enhancers Academic Background The establishment of cellular identity relies on the concerted action of multiple transcription factors (TFs) bound to enhancers of cell-type-specific genes. Although TFs recognize specific DNA motifs within accessible chromatin, this information alone is...
Scalable Production of Ultraflat and Ultraflexible Diamond Membranes Academic Background Diamond, as a material with exceptional physical properties, holds significant potential in various fields such as electronics, photonics, mechanics, thermotics, and acoustics. However, despite substantial progress in diamond research over the past decades, the...
Lithocholic Acid Phenocopies Anti-Ageing Effects of Caloric Restriction Academic Background Caloric restriction (CR) is a dietary intervention used to promote health and longevity by reducing food intake. Although CR has been shown to extend the lifespan of various organisms, the specific metabolic mechanisms behind its effects remain unclear. In p...
New Interpretation of the Moon’s Age: A Tidal Heating-Driven Remelting Event Academic Background The formation of the Moon has been a significant issue in planetary science. Currently, the most widely accepted theory for the Moon’s formation is the “Giant Impact Hypothesis,” which posits that during the late stages of Earth’s formation, a Mars-size...
Breakthrough Research on Trimodal Thermal Energy Storage Materials for Renewable Energy Applications Academic Background With the global reduction in dependence on fossil fuels, the widespread application of renewable energy has become a key focus for future energy development. However, the intermittency and instability of renewable energy make eff...
Research on Solid-State Nuclear Clocks Based on 229ThF4 Thin Films Academic Background Nuclear clocks, based on nuclear transitions, offer extremely high precision and stability. In recent years, nuclear clocks based on the thorium-229 (229Th) nuclear isomer transition have garnered significant attention. The 229Th nuclear isomer transition has an ...
Report on the Study of Diatom Phytochromes Integrating Underwater Light Spectrum to Sense Depth Academic Background The distribution of light in marine ecosystems profoundly influences aquatic life. Light not only attenuates with depth but also undergoes significant spectral changes. However, research on how phytoplankton perceive these light chang...