Neurophysiological Effects of Deep Dry Needling on Spinal Reflexes Academic Background Deep Dry Needling (DDN) is a commonly used method for treating muscle trigger points (TrPs), particularly in patients with neuromuscular pain and spasticity. Although DDN is widely used in clinical practice, its neurophysiological mechanisms are not yet fully und...
The Impact of Aging and Antioxidants on the Recovery from Spreading Depolarization in Locusts Academic Background Spreading Depolarization (SD) is a phenomenon that temporarily shuts down neural processing in both mammals and insects. In humans, SD is associated with various pathological states, such as migraine aura and neuronal death following tr...
New Findings in Visual Perception and Eye Movement Research Background Introduction In daily life, despite the constant rapid eye movements (known as saccades), we are still able to perceive a stable visual environment. This stability is achieved through the integration of information by the visual system during saccades. However, the mechanisms of...
Differential Contributions of High-Frequency Activity and C1 ERP Component to Visual Processing: A Combined EEG-MEG Study Academic Background In the field of neuroscience, understanding how visual information is processed in the brain is a central question. Visual information processing is typically divided into two main processes: feedforward and ...
Impact of GLP-1 Receptor Agonists on Axonal Function in Diabetic Peripheral Neuropathy Academic Background Diabetic Peripheral Neuropathy (DPN) is one of the most common complications in patients with type 2 diabetes worldwide, affecting approximately 50% of diabetic patients. The main symptoms of DPN include neuropathic pain, numbness, and in seve...
Isorhamnetin Ameliorates 6-OHDA-Induced SH-SY5Y Cell Damage by Targeting FosL1 to Activate the Akt/mTOR Pathway Academic Background Parkinson’s Disease (PD) is a chronic neurodegenerative disorder characterized by the loss of dopaminergic neurons in the Substantia Nigra Pars Compacta (SNpc). This neuronal loss is closely associated with mitochondri...
The Impact of Cognitive Load on Interlimb Differences in Motor Control in Older Adults Academic Background In daily life, we often observe that the dominant hand (e.g., the right hand in right-handed individuals) performs better than the non-dominant hand in simple tasks. However, these interlimb differences may be influenced by task complexity and...
New Discoveries in Cortical Motor Maps Background Introduction Humans and other primates are capable of performing a wide range of complex body movements, the initiation and control of which rely on multiple cortical and subcortical structures. Among these, the primary motor cortex (M1), located in the precentral gyrus, is the core region for execu...
Regulation of the Mevalonate Pathway in Breast Cancer and Its Role in Tumorigenesis and Lung Metastasis Background Introduction Breast cancer is one of the most common cancers among women worldwide, and its occurrence and metastasis mechanisms are complex, involving abnormal regulation of multiple signaling pathways and metabolic processes. In rece...
The Potential Role of Platelet-Activating Factor in Cancer Immunotherapy Background Cancer immunotherapy has been a significant breakthrough in cancer treatment in recent years, but its efficacy is still limited by the immunosuppressive mechanisms within the tumor microenvironment (TME). The TME supports the differentiation and proliferation of mye...