Design and Application of 4D-Printed Snake-like Biomimetic Soft Robots

Design and Application of 4D-Printed Snake-like Biomimetic Soft Robots

4D-Printed Biomimetic Snake-like Soft Robot Academic Background With advancements in medical technology, the ability of wireless microrobots to navigate complex vascular networks within living organisms has garnered significant attention. These robots can perform precise medical tasks in confined spaces, such as targeted drug delivery, endoscopic e...

Reduced Graphene Oxide-Mediated Electron–Hole Separation Using Titanium Dioxide Increases the Photocatalytic Antibacterial Activity of Bone Scaffolds

Study on Reduced Graphene Oxide-Mediated Titanium Dioxide Photocatalytic Antibacterial Bone Scaffolds Academic Background Bacterial infection is one of the most common complications following the implantation of artificial bone scaffolds during bone defect repair. Bacteria form biofilms on the scaffold surface, releasing acids and enzymes that inte...

Deep Phenotyping of Testosterone-Prompted Fibrosis in Arrhythmogenic Right Ventricular Cardiomyopathy Using iPSC-Derived Engineered Cardiac Spheroids

iPSC-Derived Engineered Cardiac Spheroids Reveal the Fibrotic Role of Testosterone in Arrhythmogenic Right Ventricular Cardiomyopathy Academic Background Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) is an inherited cardiomyopathy characterized by the replacement of myocardial tissue with adipose and fibrous tissue, leading to arrhythmias,...

Research and Clinical Applications of Selective Laser Melting Tantalum Bone Plates

Research and Clinical Applications of Selective Laser Melted Tantalum Bone Plates Academic Background In the field of orthopedic implants, titanium (Ti)-based alloys and tantalum (Ta) are widely used due to their high biocompatibility. Titanium-based alloys are typically used to manufacture load-bearing implants, such as bone plates and femoral ste...

Photothermal MXene-Embedded Tannin–Eu3+ Particles as In Situ Bacterial Vaccines for Accelerating Healing of Wounds Infected by Seawater Immersion and Providing Persistent Anti-Infection Effects

Photothermal MXene-Embedded Tannin-Eu³⁺ Particles as In Situ Bacterial Vaccines for Seawater-Immersed Infected Wounds Academic Background Seawater-immersed wounds are prone to severe infections due to the low temperature, high salinity, and bacteria-rich environment, which hinder wound healing. Traditional antibacterial strategies often fail to pro...

3D Bioprinting of a Dermal Scaffold for Full-Thickness Skin Tissue Regeneration

3D Bioprinting of Dermal Scaffolds for Full-Thickness Skin Tissue Regeneration Academic Background The skin, being the largest organ of the human body, plays a crucial role in defending against external environmental damage and preventing microbial invasion. However, when the skin suffers extensive damage, its self-repair capabilities are limited, ...

Enhancing Angiogenesis and Osseointegration through a Double Gyroid Ti6Al4V Scaffold with Triply Periodic Minimal Surface

Application of Double Gyroid Titanium Alloy Scaffolds Based on Triply Periodic Minimal Surface Structures in Bone Repair Academic Background Bone defect repair is a significant challenge in the field of orthopedics, especially in cases of critical-size bone defects caused by trauma, tumors, inflammation, and other diseases. Currently, the commonly ...

Magnesium and Gallium-Co-loaded Microspheres Accelerate Bone Repair via Osteogenesis and Antibiosis

Research on Magnesium and Gallium Co-loaded Microspheres Accelerating Bone Repair Academic Background Bone defects are a common clinical challenge, often caused by infection, tumor resection, or mechanical trauma. Bone defects not only affect patients’ quality of life but may also lead to functional loss. Although bone grafting is currently the pri...

Novel Heart Valve Leaflet Designs with Stiff Polymeric Materials and Biomimetic Kinematics

Novel Heart Valve Leaflet Design: Research Based on High-Stiffness Polymeric Materials and Biomimetic Kinematics Academic Background Heart valve disease is a significant global health issue, with over 850,000 patients requiring heart valve replacement surgery annually. Currently, the heart valves used in clinical practice are mainly divided into tw...

Cav3.3-Mediated Endochondral Ossification in a Three-Dimensional Bioprinted GelMA Hydrogel

Cav3.3-Mediated Endochondral Ossification in a Three-Dimensional Bioprinted GelMA Hydrogel

Study on Cav3.3-Mediated Endochondral Ossification in 3D Bioprinted GelMA Hydrogel Research Background Bone development is a complex process, in which the growth plate (GP) plays a crucial role in the longitudinal growth of long bones. The growth plate regulates bone maturation through the process of endochondral ossification (EO). However, GP dysf...