Early Malnutrition and the Risk of Osteoporosis in Adulthood: A Large-Scale Cross-Sectional Study Academic Background Osteoporosis is a chronic, systemic metabolic bone disease characterized by reduced bone density and deterioration of bone microstructure, leading to a significantly increased risk of fractures. Globally, approximately 9 million fra...

Postoperative Complications of Cervical Spinal Fusion in Diabetic Patients: A Retrospective Study Background Diabetes Mellitus (DM) is a globally prevalent chronic condition that significantly impacts surgical outcomes, particularly in spine surgery. Diabetic patients face a higher risk of postoperative complications. However, over the past decade,...

Comparative Study of Robotic-Assisted Thyroidectomy versus Traditional Open Surgery in Thyroid Cancer Treatment Academic Background The incidence of thyroid cancer has been increasing annually, with differentiated thyroid carcinoma (DTC) accounting for over 90% of all thyroid cancer cases. Currently, the standard treatment for DTC includes surgical...

Innovative Surgical Strategies for Reoperation of Local Recurrence in Renal Cell Carcinoma Academic Background Renal cell carcinoma (RCC) is one of the most common malignant tumors in adults, accounting for 5% of malignancies in males and 3% in females. Although surgery remains the standard treatment for localized RCC, nephron-sparing surgery (NSS)...

Investigating the Validity of mCIM and sCIM Phenotypic Methods in Screening Pseudomonas aeruginosa Isolates Producing IMP, VIM, and NDM Metallo-β-Lactamases from Burn Wounds Background Pseudomonas aeruginosa is a Gram-negative bacterium widely found in the environment, particularly in hospital settings. It is the second most common pathogen causing...

Aztreonam-Avibactam Activity Against Multidrug-Resistant Klebsiella pneumoniae Complex Background The Klebsiella pneumoniae complex (KPC) is a group of opportunistic pathogens that pose a serious threat to public health. In recent years, the infection rate of multidrug-resistant (MDR) Klebsiella pneumoniae has significantly increased, leading to ex...

Novel Benzene-Containing Polyketides and Modified Diketopiperazine from Actinomycete of the Genus Cryptosporangium Academic Background Microbial natural products hold significant value in drug development, particularly actinomycetes, which provide a rich source of various therapeutic compounds, such as aminoglycosides, macrolides, and tetracyclines...

Therapeutic Potential of Isoallolithocholic Acid in Methicillin-Resistant Staphylococcus aureus Peritoneal Infection Background Methicillin-resistant Staphylococcus aureus (MRSA), discovered in 1961, has become one of the most common antibiotic-resistant bacteria worldwide. MRSA infections can lead to fatal sepsis, pneumonia, and high rates of skin...

Study on the Combination of Cefiderocol and Tetracycline Analogues for Treating Carbapenem-Resistant Acinetobacter baumannii Academic Background Carbapenem-resistant Acinetobacter baumannii (CR-AB) is one of the major pathogens responsible for hospital-acquired infections, often leading to severe conditions such as ventilator-associated pneumonia, ...

New Hope for the Treatment of Non-Tuberculous Mycobacterial Diseases—Research on Acetohydroxyacid Synthase Inhibitors Academic Background Non-tuberculous mycobacteria (NTM) infections have become an important cause of pulmonary diseases worldwide in recent years, especially among immunocompromised populations. The treatment of NTM infections faces ...