Report: Revealing White Matter Changes Associated with Tau in Early Alzheimer’s Disease through Fixel-based Analysis Research Background Alzheimer’s Disease (AD) is generally thought to primarily affect the grey matter (GM), but more and more evidence shows that the white matter (WM) also experiences abnormalities. Current research largely relies o...
Development and Standardization of an Osteoradionecrosis Classification System in Head and Neck Cancer: Implementation Based on Risk Model In recent years, the side effects brought by the treatment of head and neck cancer (HNC), especially radiotherapy, have become a focal point of academic attention. Osteoradionecrosis (ORN) is one of the most sev...
Background Myelodysplastic Syndromes (MDS) are a group of heterogeneous diseases originating from bone marrow hematopoietic stem cells, characterized by reduced blood cell production. Although certain progress in treatment has been made in recent years, allogeneic hematopoietic stem-cell transplantation (HSCT) remains the only potentially curative ...
Incidence of Hormone-Related Cancers and Intimate Care Products Introduction In recent years, there has been an increasing concern about the safety of intimate care products that may contain potential endocrine disrupting chemicals, such as phthalates, parabens, and bisphenols. These chemicals are believed to alter endogenous hormone levels, influe...
Multicenter Prospective Study: Feasibility of Electronic Patient-Reported Outcomes (ePROs) in Elderly Cancer Patients Research Background In recent years, telemedicine has developed rapidly, especially during the COVID-19 pandemic, and is considered a solution to the problem of medical personnel shortages. Electronic patient-reported outcomes (ePRO...
Background Introduction Diffusion Tensor Magnetic Resonance Imaging (DTI) is a widely used neuroimaging technique for imaging the microstructure of brain tissues and white matter tracts. However, noise in Diffusion-Weighted Images (DWI) can reduce the accuracy of microstructural parameters derived from DTI data and also necessitate longer acquisiti...
DeepDTI: High-Fidelity Six-Direction Diffusion Tensor Imaging Using Deep Learning Research Background and Motivation Diffusion Tensor Imaging (DTI) boasts unparalleled advantages in mapping the microstructure and structural connectivity of live human brain tissue. However, traditional DTI techniques require extensive angular sampling, leading to pr...
Parkinson’s Disease (PD) is a neurodegenerative disease primarily characterized by dopaminergic neuron damage. Aside from causing motor disorders, over 80% of Parkinson’s disease patients also suffer from sleep disorders. Fragmented sleep is a common type of sleep disturbance among PD patients. It is associated not only with sleep maintenance insom...
Research Report: Predictive Role of Cerebrospinal Fluid Routine Parameters in the Disease Process of Multiple Sclerosis Background Multiple Sclerosis (MS) is characterized by a highly variable and unpredictable disease course. In the diagnosis of MS, cerebrospinal fluid (CSF) analysis is often a standard procedure. However, there has been ongoing d...
The Opening of the Blood-Brain Barrier in the Nigrostriatal System in Parkinson’s Disease Research Background Parkinson’s disease is a neurodegenerative disorder characterized by the gradual degeneration of dopaminergic neurons in the substantia nigra pars compacta, leading to impaired dopaminergic transmission in the striatum. Currently, there are...