In this academic paper, the authors attempt to address the common headache complication during magnetic resonance-guided focused ultrasound (mrgFUS) treatment. Headache is a common complication, and in severe cases, it may even cause patients to be unable to tolerate ultrasound radiation and terminate the treatment. There is currently no establishe...
This is a report on the 55-year follow-up of the first case of a craniopharyngioma patient who underwent gamma knife radiosurgery. The article details the medical history, diagnosis process, gamma knife surgery details, as well as the 55-year follow-up with multiple treatments, providing a comprehensive overview of the patient’s long medical journe...
Vertebral hemangiomas are the most common primary tumors of the spine. Most vertebral hemangiomas are asymptomatic benign lesions, but in a few cases, if the mass grows and extends into the epidural space, compressing the spinal cord or nerve roots, it may lead to neurological symptoms such as pain, sensory abnormalities, or motor deficits. The tre...
Outcomes of Mechanical Thrombectomy for Stroke Patients with Low Alberta Stroke Program Early CT Score Background Acute ischemic stroke is a life-threatening disease, and large vessel occlusion is one of the major causes of severe disability. Mechanical thrombectomy (MT) has become the standard treatment for acute ischemic stroke, with multiple cli...
Sagittal Imbalance Patterns in Degenerative Kyphosis of the Lumbar or Thoracolumbar Spine and Their Impact on Postoperative Complications Research Background Degenerative kyphosis (DK) is the most common type of spinal deformity in the elderly. Sagittal imbalance is a typical radiological feature of DK and is associated with a severe decline in qua...
This is a report on a new classification method for caudal agenesis: Caudal agenesis is a congenital disorder characterized by the absence of lower vertebrae. Previous classifications of caudal agenesis were primarily based on the level of bony deficiency or the position of the terminal spinal cord, but there has been debate as to whether these cla...
Correlation between Task Complexity and Accuracy of Cortical Language Mapping Introduction This study aimed to investigate whether task complexity affects the accuracy of mapping language functions during direct cortical stimulation mapping (DCS). The researchers hypothesized that due to the reduced computational ability of neurons in the cortex in...
This study revolves around the protein arginine methyltransferase PRMT9, revealing its important role in acute myeloid leukemia (AML) and its potential as an anticancer target. Researchers found that PRMT9 expression levels were significantly elevated in AML stem cells and leukemic cells. Through gene editing and chemical probes, they discovered th...
The 5’ untranslated region (5’UTR) is a regulatory region at the start of messenger RNA (mRNA) molecules, playing a crucial role in regulating the translation process and affecting protein expression levels. Language models have demonstrated effectiveness in decoding protein and genomic sequence functions. In this study, the authors introduce a lan...
This study utilized a machine learning framework to explore the underlying cell states and cellular ecosystems constituting soft tissue sarcomas, and associated them with patient prognosis and response to immunotherapy. Research Background: Soft tissue sarcomas are rare and highly heterogeneous malignancies of connective tissues, with limited syste...