Integrated Analysis of Blood DNA Methylation, Genetic Variation, Circulating Proteins, microRNAs, and Kidney Failure in Type 1 Diabetes Research Background Diabetic Kidney Disease (DKD) is one of the major complications of Type 1 Diabetes (T1D). Approximately 40% of T1D patients develop DKD, and 10% to 15% eventually progress to Kidney Failure (KF)...

Deep Reinforcement Learning Empowers Agile Soccer Skills for Bipedal Robots Background Introduction One of the long-term goals of artificial intelligence (AI) research is to enable agents to exhibit agility, flexibility, and understanding in the physical world. However, animals and humans not only smoothly complete complex physical actions but also...

Scientists Reveal the Anti-Tumor Mechanism of Src Inhibitors in IDH Mutant Cholangiocarcinoma Background Introduction In recent years, the incidence of intrahepatic cholangiocarcinoma (ICC) has been rising worldwide. ICC is a highly invasive tumor usually lacking noticeable symptoms in the early stages, with cases often being inoperable by the time...

Autonomous Navigation and Walking Wheel-Leg Robot Background Introduction The acceleration of urbanization has posed significant challenges for supply chain logistics, especially for last-mile delivery. As traffic pressure increases and the demand for faster delivery services rises, particularly with complex routes indoors and on city streets, trad...

High-Fidelity Fatigue-Resistant Muscle Control Through Closed-Loop Optogenetic Neural Modulation Background Introduction Skeletal muscle is the biological actuator for almost all movements in animals and humans. However, under various neurological conditions, the communication pathways between the central nervous system and neuromuscular components...

Liver Danger Signal Triggers TREM2+ Macrophage-Mediated MS4A7-Dependent Inflammasome Activation Driving Steatohepatitis Background and Research Motivation In recent years, with the increasing incidence of metabolic dysfunction-associated steatohepatitis (MASH), its pathological mechanisms have garnered significant attention. MASH, formerly known as...

Stereoscopic Artificial Compound Eyes for Spatiotemporal Perception in Three-Dimensional Space This research article was published on May 15, 2024, in the journal Science Robotics, titled “Stereoscopic Artificial Compound Eyes for Spatiotemporal Perception in Three-Dimensional Space.” The first author is Byungjoon Bae, and the corresponding author ...

Real-World Humanoid Robot Walking Based on Reinforcement Learning Background Introduction Humanoid robots have enormous potential for autonomous operation in diverse environments, not only alleviating labor shortages in factories but also assisting elderly people at home and exploring new planets. Although classical controllers show excellent effec...

Ultra-wide Field-of-view Pinhole Compound Eye Based on Hemispherical Nanowire Array for Robotic Vision In the rapid development of contemporary artificial intelligence and robotics technology, the visual system, as a crucial component, has attracted widespread attention and in-depth research. According to a research paper published by Zhou et al. o...

Simultaneously Recording Up to a Million Neurons’ Cortical Dynamics Reveals Unbounded Scaling of Neuronal Quantity and Dimensionality Summary This scientific report titled “Simultaneously Recording Up to a Million Neurons’ Cortical Dynamics Reveals Unbounded Scaling of Neuronal Quantity and Dimensionality,” published in the journal Neuron (Volume 1...