Modulation of Electrical Synapses and Excitability by Dopamine Receptors in the Thalamic Reticular Nucleus Academic Background The Thalamic Reticular Nucleus (TRN) is a thin shell of γ-aminobutyric acid (GABA)ergic inhibitory neurons in the thalamus. These neurons are coupled via gap junctions and regulate the transmission of sensory information fr...

Increased Robustness and Adaptation of the Crab Pyloric Rhythm to Simultaneous Temperature and Elevated Extracellular Potassium Academic Background In nature, animals often face multiple simultaneous environmental perturbations, which may include temperature fluctuations, pH variations, salinity changes, and alterations in extracellular potassium c...

Study on the Discharge Characteristics of Motor Neurons Innervating Paralyzed Muscles after Spinal Cord Injury Academic Background Spinal Cord Injury (SCI) is a severe neurological injury that typically leads to the loss of motor and sensory functions below the injury level. Although patients clinically diagnosed with complete SCI are considered un...

Effects of Repeated Social Stress on Neuronal Activity in the Posterior Medial Amygdala of Male Rats Background Social stress plays a crucial role in social behavior and mental health. Chronic social stress not only leads to changes in individual behavior but is also closely related to the development of various psychiatric disorders, such as anxie...

Research on Transcranial Direct Current Stimulation Over Vagus Nerve for Post-Stroke Dysphagia Academic Background Stroke is the second leading cause of death worldwide, and survivors often face a range of complications, among which dysphagia is particularly common, with an incidence rate ranging from 27% to 64%. Dysphagia can lead to serious probl...

Academic Background The visual system is a crucial component for animals to perceive their external environment, and research on its development and function is essential for understanding the sensory mechanisms of mammals. However, traditional studies have predominantly relied on nocturnal or crepuscular laboratory rodents, such as mice, rats, and...

Research on Motor Decision-Making under Uncertainty and Time Pressure Academic Background In daily life, animals and humans often need to choose the most appropriate action from multiple possible options. However, how to plan and execute these actions under conditions of goal uncertainty and time pressure remains an incomplete question in neuroscie...

5-HT7R Enhances Neuroimmune Resilience and Alleviates Meningitis by Promoting CCR5 Ubiquitination Academic Background Bacterial meningitis is a rapidly onset, highly fatal disease with epidemic potential, especially when caused by Streptococcus pneumoniae (S.p.) infection. The destruction of the blood-brain barrier (BBB) leads to the release of inf...

Modular Brain-Machine Interface: Innovative Breakthrough in Neurorecording, Neurostimulation, and Drug Delivery Academic Background Brain-Machine Interfaces (BMIs) are crucial tools in neuroscience and clinical medicine, enabling interactions between the brain and the external world through charge, matter, and information exchange. They are widely ...

Improving Glioblastoma Treatment with Imaging, Radiotherapy, Drug Delivery, and Therapeutic Systems Academic Background Glioblastoma (GBM) is the most common and aggressive type of brain cancer, with an extremely poor prognosis and a five-year survival rate of less than 10%. Despite decades of extensive research in drug therapy, radiation therapy, ...