This research explores the clinical value of plasma phosphorylated tau proteins (p-tau) 217 and 181 in assessing patients with mild cognitive impairment. Mild cognitive impairment may be a precursor stage of Alzheimer’s disease (AD), and early detection and monitoring of disease progression are crucial for disease management. Research Background: A...
This is a large-scale prospective cohort study on depression in patients with Parkinson’s disease (PD). Researchers have used the vast cohort data from the UK Biobank to investigate the temporal association between depression and the onset of PD, the relationship between depression and brain region structure in PD patients, and the impact of depres...
Age-related hearing loss is considered a modifiable risk factor for dementia. However, the relationship between hearing, neurodegenerative changes, and cognitive changes, as well as how pathological processes such as Alzheimer’s disease and cerebrovascular disease affect these relationships, is not yet well understood. This report details a study o...
Epidemiological Study of Intimate Partner and Domestic Violence-Related Traumatic Brain Injuries in the United States from 2018-2021 Background Intimate partner violence (IPV) and domestic violence (DV) have severe medical, social, and legal consequences for victims. These violent events often result in traumatic brain injuries (TBIs), further exac...
This study explored the value of arterial wall enhancement grading on magnetic resonance imaging in predicting disease progression of moyamoya disease. This was a single-center retrospective cohort study that included 48 patients diagnosed with moyamoya disease who underwent arterial wall imaging and digital subtraction angiography follow-up. The s...
Study on the Extent of Resection Threshold in Different Molecular Subtypes of Newly Diagnosed IDH-wildtype Glioblastoma Introduction Glioblastoma (GBM) is the most common malignant brain tumor in adults. Although surgical resection, radiotherapy, and chemotherapy are the current standard treatment regimens, the prognosis of GBM remains poor, with a...
In this academic paper, the authors attempt to address the common headache complication during magnetic resonance-guided focused ultrasound (mrgFUS) treatment. Headache is a common complication, and in severe cases, it may even cause patients to be unable to tolerate ultrasound radiation and terminate the treatment. There is currently no establishe...
This is a report on the 55-year follow-up of the first case of a craniopharyngioma patient who underwent gamma knife radiosurgery. The article details the medical history, diagnosis process, gamma knife surgery details, as well as the 55-year follow-up with multiple treatments, providing a comprehensive overview of the patient’s long medical journe...
Vertebral hemangiomas are the most common primary tumors of the spine. Most vertebral hemangiomas are asymptomatic benign lesions, but in a few cases, if the mass grows and extends into the epidural space, compressing the spinal cord or nerve roots, it may lead to neurological symptoms such as pain, sensory abnormalities, or motor deficits. The tre...
Outcomes of Mechanical Thrombectomy for Stroke Patients with Low Alberta Stroke Program Early CT Score Background Acute ischemic stroke is a life-threatening disease, and large vessel occlusion is one of the major causes of severe disability. Mechanical thrombectomy (MT) has become the standard treatment for acute ischemic stroke, with multiple cli...