Sex Differences in the Extent of Acute Axonal Pathologies After Experimental Concussion

Gender Differences in Acute Axonal Pathology Following Experimental Concussion Academic Background Each year, approximately 50 million people worldwide suffer from concussions, also known as mild traumatic brain injuries (TBI). However, for more than 15% of patients, this “mild” brain injury can lead to lasting neurocognitive dysfunction. The exist...

Towards Machine Learning-Based Quantitative Hyperspectral Image Guidance for Brain Tumor Resection

Towards Machine Learning-Based Quantitative Hyperspectral Image Guidance for Brain Tumor Resection

Study on the Role of Machine Learning-Assisted Quantitative Hyperspectral Imaging in Brain Tumor Resection Background Introduction Complete resection of malignant gliomas has always been challenged by the difficulty of distinguishing tumor cells in invasive regions. The background of this study is: In neurosurgery, the application of 5-aminolevulin...

AI-Powered Radiomics Algorithm Based on Slice Pooling for the Glioma Grading

AI-Powered Radiomics Algorithm Based on Slice Pooling for the Glioma Grading

AI-Assisted Radiomics Algorithm for Glioma Grading Based on Slice Pooling Background Introduction Glioma is the most common and threatening tumor in the central nervous system, characterized by high incidence, high recurrence rates, high mortality, and low cure rates. The World Health Organization (WHO) classifies gliomas into four grades (I, II, I...

Noninvasive Grading of Glioma by Knowledge Distillation Based Lightweight Convolutional Neural Network

Review of Non-Invasive Glioma Grading Research: Lightweight Convolutional Neural Networks Based on Knowledge Distillation Background Gliomas are the main tumors of the central nervous system, and early detection is crucial. The World Health Organization (WHO) classifies gliomas from grade I to IV, with grades I and II being low-grade gliomas (LGG) ...

CaNet: Context Aware Network for Brain Glioma Segmentation

CaNet: Context Aware Network for Brain Glioma Segmentation

Context-Aware Network Study Report for Glioma Segmentation Glioma is a common type of adult brain tumor that severely harms health and has a high mortality rate. To provide sufficient evidence for early diagnosis, surgical planning, and postoperative observation, multimodal Magnetic Resonance Imaging (MRI) has been widely applied in this field. The...

First Clinical Investigation of Near-Infrared Window IIA/IIB Fluorescence Imaging for Precise Surgical Resection of Gliomas

First Clinical Investigation of Near-Infrared Window IIA/IIB Fluorescence Imaging for Precise Surgical Resection of Gliomas

“IEEE Transactions on Biomedical Engineering” August 2022, Vol. 69, No. 8, First Clinical Study: Application of Near-Infrared Window IIA/IIB Fluorescence Imaging in Precise Glioma Resection Surgery Cao Caiguang, Jin Zeping, Shi Xiaojing, Zhang Zhe, Xiao Anqi, Yang Junying, Ji Nan, Tian Jie (IEEE Member), Hu Zhenhua (IEEE Senior Member) Introduction...

Near-Infrared Window II Fluorescence Image-Guided Surgery of High-Grade Gliomas Prolongs the Progression-Free Survival of Patients

Near-Infrared Window II Fluorescence Image-Guided Surgery of High-Grade Gliomas Prolongs the Progression-Free Survival of Patients

Near-Infrared Window II Fluorescence Imaging-Guided Surgery Prolongs Progression-Free Survival for High-Grade Glioma Patients Research Background High-grade glioma (HGG) is the most common malignant primary tumor in the central nervous system, with glioblastoma (GBM) having the worst prognosis. To improve the treatment outcomes for GBM patients, in...

The Necessity of Human Ventromedial Prefrontal Cortex in Prosocial Motivation

The Necessity of the Human Ventromedial Prefrontal Cortex for Prosocial Motivation Research Background and Motivation The ventromedial prefrontal cortex (vmPFC) plays a crucial role in decision-making processes. Functional neuroimaging studies indicate that the vmPFC is key in handling rewards and efforts and is also associated with prosocial behav...

Multisensory Flicker Modulates Widespread Brain Networks and Reduces Interictal Epileptiform Discharges

Multisensory Flicker Modulates Widespread Brain Networks and Reduces Interictal Epileptiform Discharges

Research Report on Multi-sensory Flicker Regulating Extensive Brain Networks and Reducing Interictal Epileptiform Discharges Background Introduction In treating neurological disorders, modulating brain oscillations has great potential. Non-invasive interventions, suitable for everyday use at home, have become the focus of the scientific community, ...

A prognostic neural epigenetic signature in high-grade glioma

Study of Neuroepithelial Genetic Markers and Prognosis in High-Grade Gliomas Background and Research Motivation High-grade gliomas are highly malignant brain tumors with generally poor patient prognosis. Previous preclinical model studies have suggested that interactions between neural and tumor cells drive tumor growth, but clinical validation of ...