Improving Glioblastoma Treatment with Imaging, Radiotherapy, Drug Delivery, and Therapeutic Systems Academic Background Glioblastoma (GBM) is the most common and aggressive type of brain cancer, with an extremely poor prognosis and a five-year survival rate of less than 10%. Despite decades of extensive research in drug therapy, radiation therapy, ...
Exploring the Applications of Single-Molecule Systems for Detection and Monitoring of Plasma-Circulating Nucleosomes and Oncoproteins in Diffuse Midline Glioma Research Background and Problem Overview Diffuse Midline Glioma (DMG) is a highly aggressive brain tumor primarily affecting children with extremely high mortality rates. This type of tumor ...
Research Report on Automated Robotic Craniotomy Surgery System Background As the central organ of complex life activities, the brain governs all psychological and conscious processes, playing a crucial role in every aspect of life. Entering the 21st century, neuroscience has become one of the fastest-growing and most prominent fields, with animal m...
Research on 3D Bioprinted Scaffolds Promoting Bone Regeneration Academic Background In recent years, the incidence of head and craniofacial injuries has significantly increased due to the development of industries and transportation, as well as the frequent occurrence of wars and conflicts. These injuries and related treatments (such as decompressi...
Global Burden of Mild Traumatic Brain Injury: 1990-2019 Academic Background Mild traumatic brain injury (MTBI) is a common global health issue, particularly prevalent among the elderly population. MTBI not only causes symptoms such as headaches, dizziness, and fatigue but may also lead to long-term cognitive impairments, mood swings, and sleep diso...
Immunogenicity and Therapeutic Challenges of IDH-Mutant Gliomas Background Glioma is a common central nervous system tumor, and its treatment and prognosis vary significantly depending on molecular characteristics. In recent years, the diagnostic and prognostic significance of isocitrate dehydrogenase (IDH) mutations in gliomas has been increasingl...
Cellular Network Connectivity and Therapeutic Strategies in Malignant Brain Tumors Academic Background Malignant brain tumors, particularly glioblastoma, are among the most aggressive and lethal tumors in the central nervous system. Despite significant advancements in tumor biology and treatment methods in recent years, the median survival for glio...
Epigenetic Diversity in Glioblastoma Academic Background Glioblastoma is the most common primary malignant brain tumor. Despite decades of research, its prognosis remains extremely poor, with an average survival of only 14 months after diagnosis. The significant heterogeneity of glioblastoma is one of the main reasons for the slow progress in its t...
Microglia and Macrophages in Glioblastoma Academic Background Glioblastoma (GBM) is the most common primary malignant tumor of the central nervous system, characterized by high invasiveness and lethality. Despite standard treatments such as surgery, chemotherapy, and radiotherapy, the survival rate of patients remains extremely limited, with a medi...
Latest Research on Epilepsy-Associated Tumors: Classification and Animal Models Background Epilepsy is a common neurological disorder, and some patients are accompanied by brain tumors, particularly low-grade neuroepithelial tumors (LGNTs). These tumors typically grow slowly but are highly associated with drug-resistant epilepsy. Although research ...