Application of Radiomics in Predicting Local Control in Postoperative Stereotactic Radiotherapy for Brain Metastasis Patients Academic Background Brain Metastases (BMs) are the most common malignant brain tumors, far surpassing primary brain tumors like gliomas in incidence. Recent medical guidelines recommend surgical treatment for patients with s...
Comprehensive Analysis of Leptomeningeal Metastasis in IDH Wild-Type Glioblastoma In this article published in the journal “Neuro-Oncology,” the research team starting in 2024 delves into the incidence, risk factors, and prognosis of leptomeningeal metastases (LM) in patients with isocitrate dehydrogenase (IDH) wild-type glioblastoma. This study wa...
International Consensus on Resistance, Rebound, and Recurrence in Pediatric Low-Grade Glioma with MAPK Inhibition Therapy: Established Using a Modified Delphi Method Academic Background Pediatric low-grade glioma (PLGG) is the most common type of tumor in the central nervous system of children. Although these tumors have a relatively high overall s...
Microcirculatory Disorders of Cerebral Blood Flow and the Hypoxic-Ischemic Microenvironment Related to Brain Metastasis Development Background and Research Motivation Brain metastasis (BM) is an increasing challenge in oncology due to its severe impact on neurological function, limited treatment options, and resulting poor prognosis. BM develops th...
Analysis of Risk Factors Related to Specific Domain Neurocognitive Outcomes in Pediatric Survivors of Posterior Fossa Brain Tumors – HIT 2000 Trial Results Research Background Brain tumors are the most common solid tumors in childhood, particularly central nervous system (CNS) tumors. Studies have shown that patients who receive craniospinal irradi...
Wireless Injectable Ultrasound Sensor for Intracranial Signal Monitoring Background Introduction Direct and accurate monitoring of intracranial physiological conditions is extremely important for injury classification, prognosis assessment, and disease prevention. However, traditional wired clinical devices, such as percutaneous leads, although per...
Sustained Reduction of Essential Tremor with Low-Power Non-Thermal Transcranial Focused Ultrasound Stimulation in Humans Background Essential Tremor (ET) is one of the most common neurological disorders, primarily characterized by bilateral upper limb action tremor that persists for more than three years. For ET unresponsive to medication, neurosur...
Patients with Parkinson’s Disease (PD) often experience gait impairments, which severely affect their quality of life. Previous studies have suggested that β-frequency (15-30 Hz) oscillatory activity in the basal ganglia may be associated with gait impairments, but the exact dynamics of these oscillations during the gait process remain unclear. Add...
Application of Non-Invasive Vagus Nerve Stimulation in Spontaneous Subarachnoid Hemorrhage: A Randomized Safety and Feasibility Study Report Spontaneous subarachnoid hemorrhage (SAH) is often accompanied by severe thunderclap headaches, which patients typically describe as the “worst headache of their lives.” The vast majority of patients (90%) con...
Study on Cerebral Amyloid Angiopathy (CAA) and the Level of Tight Junction Protein Claudin-5 in Microvessels Background Cerebral Amyloid Angiopathy (CAA) is a disease caused by the deposition of Amyloid-β (Aβ) in the cerebral blood vessels. Research indicates that approximately 23% of individuals over the age of 55 have moderate to severe CAA. CAA ...