Turning the Operating Room into a Mixed-Reality Environment: A Prospective Clinical Investigation for Cerebral Aneurysm Clipping

Turning the Operating Room into a Mixed-Reality Environment: A Prospective Clinical Investigation for Cerebral Aneurysm Clipping

Transforming the Operating Room into a Mixed Reality Environment: A Prospective Clinical Study on Aneurysm Clipping The surgical treatment of cerebral aneurysms is a highly complex and delicate process in neurosurgery. Researchers continue to explore new technologies and methods to improve surgical outcomes. In recent years, the development of Mixe...

Radiomics-based Prediction of Local Control in Patients with Brain Metastases Following Postoperative Stereotactic Radiotherapy

Application of Radiomics in Predicting Local Control in Postoperative Stereotactic Radiotherapy for Brain Metastasis Patients Academic Background Brain Metastases (BMs) are the most common malignant brain tumors, far surpassing primary brain tumors like gliomas in incidence. Recent medical guidelines recommend surgical treatment for patients with s...

Leptomeningeal Metastases in IDH-Wildtype Glioblastomas Revisited: Comprehensive Analysis of Incidence, Risk Factors, and Prognosis Based on Post-Contrast FLAIR

Comprehensive Analysis of Leptomeningeal Metastasis in IDH Wild-Type Glioblastoma In this article published in the journal “Neuro-Oncology,” the research team starting in 2024 delves into the incidence, risk factors, and prognosis of leptomeningeal metastases (LM) in patients with isocitrate dehydrogenase (IDH) wild-type glioblastoma. This study wa...

Resistance, Rebound, and Recurrence Regrowth Patterns in Pediatric Low-Grade Glioma Treated by MAPK Inhibition: A Modified Delphi Approach to Build International Consensus

International Consensus on Resistance, Rebound, and Recurrence in Pediatric Low-Grade Glioma with MAPK Inhibition Therapy: Established Using a Modified Delphi Method Academic Background Pediatric low-grade glioma (PLGG) is the most common type of tumor in the central nervous system of children. Although these tumors have a relatively high overall s...

Disturbance in Cerebral Blood Microcirculation and Hypoxic-Ischemic Microenvironment are Associated with the Development of Brain Metastasis

Microcirculatory Disorders of Cerebral Blood Flow and the Hypoxic-Ischemic Microenvironment Related to Brain Metastasis Development Background and Research Motivation Brain metastasis (BM) is an increasing challenge in oncology due to its severe impact on neurological function, limited treatment options, and resulting poor prognosis. BM develops th...

Risk Factors for Domain-Specific Neurocognitive Outcome in Pediatric Survivors of a Brain Tumor in the Posterior Fossa – Results of the HIT 2000 Trial

Analysis of Risk Factors Related to Specific Domain Neurocognitive Outcomes in Pediatric Survivors of Posterior Fossa Brain Tumors – HIT 2000 Trial Results Research Background Brain tumors are the most common solid tumors in childhood, particularly central nervous system (CNS) tumors. Studies have shown that patients who receive craniospinal irradi...

Injectable Ultrasonic Sensor for Wireless Monitoring of Intracranial Signals

Injectable Ultrasonic Sensor for Wireless Monitoring of Intracranial Signals

Wireless Injectable Ultrasound Sensor for Intracranial Signal Monitoring Background Introduction Direct and accurate monitoring of intracranial physiological conditions is extremely important for injury classification, prognosis assessment, and disease prevention. However, traditional wired clinical devices, such as percutaneous leads, although per...

Sustained Reduction of Essential Tremor with Low-Power Non-Thermal Transcranial Focused Ultrasound Stimulations in Humans

Sustained Reduction of Essential Tremor with Low-Power Non-Thermal Transcranial Focused Ultrasound Stimulations in Humans

Sustained Reduction of Essential Tremor with Low-Power Non-Thermal Transcranial Focused Ultrasound Stimulation in Humans Background Essential Tremor (ET) is one of the most common neurological disorders, primarily characterized by bilateral upper limb action tremor that persists for more than three years. For ET unresponsive to medication, neurosur...

Auditory Cues Modulate the Short Timescale Dynamics of STN Activity During Stepping in Parkinson’s Disease

Patients with Parkinson’s Disease (PD) often experience gait impairments, which severely affect their quality of life. Previous studies have suggested that β-frequency (15-30 Hz) oscillatory activity in the basal ganglia may be associated with gait impairments, but the exact dynamics of these oscillations during the gait process remain unclear. Add...

Safety and Feasibility Study of Non-Invasive Vagus Nerve Stimulation in Spontaneous Subarachnoid Hemorrhage

Application of Non-Invasive Vagus Nerve Stimulation in Spontaneous Subarachnoid Hemorrhage: A Randomized Safety and Feasibility Study Report Spontaneous subarachnoid hemorrhage (SAH) is often accompanied by severe thunderclap headaches, which patients typically describe as the “worst headache of their lives.” The vast majority of patients (90%) con...