Circuit-Based Neuromodulation Enhances Delayed Recall Ability in Patients with Mild Cognitive Impairment Introduction As the aging population increases, amnestic mild cognitive impairment (AMCl) is receiving more attention. AMCl is seen as an important transitional stage from normal cognitive function to dementia and is a hotspot for studying cogni...

This research explores the clinical value of plasma phosphorylated tau proteins (p-tau) 217 and 181 in assessing patients with mild cognitive impairment. Mild cognitive impairment may be a precursor stage of Alzheimer’s disease (AD), and early detection and monitoring of disease progression are crucial for disease management. Research Background: A...

This is a large-scale prospective cohort study on depression in patients with Parkinson’s disease (PD). Researchers have used the vast cohort data from the UK Biobank to investigate the temporal association between depression and the onset of PD, the relationship between depression and brain region structure in PD patients, and the impact of depres...

Age-related hearing loss is considered a modifiable risk factor for dementia. However, the relationship between hearing, neurodegenerative changes, and cognitive changes, as well as how pathological processes such as Alzheimer’s disease and cerebrovascular disease affect these relationships, is not yet well understood. This report details a study o...

Epidemiological Study of Intimate Partner and Domestic Violence-Related Traumatic Brain Injuries in the United States from 2018-2021 Background Intimate partner violence (IPV) and domestic violence (DV) have severe medical, social, and legal consequences for victims. These violent events often result in traumatic brain injuries (TBIs), further exac...

This study explored the value of arterial wall enhancement grading on magnetic resonance imaging in predicting disease progression of moyamoya disease. This was a single-center retrospective cohort study that included 48 patients diagnosed with moyamoya disease who underwent arterial wall imaging and digital subtraction angiography follow-up. The s...

Safety and Efficacy of Intrathecal Drug Delivery Pumps for Intractable Pain in Cancer Patients Introduction Pain management in cancer patients is a critical issue in palliative care, as clinicians strive to improve patients’ quality of life and alleviate their suffering. Most cancer patients experience cancer-related pain, and 30%-40% of them suffe...

Study on the Extent of Resection Threshold in Different Molecular Subtypes of Newly Diagnosed IDH-wildtype Glioblastoma Introduction Glioblastoma (GBM) is the most common malignant brain tumor in adults. Although surgical resection, radiotherapy, and chemotherapy are the current standard treatment regimens, the prognosis of GBM remains poor, with a...

This is a report on a scholarly article regarding the treatment results of low-bypass surgery for 215 patients with intracranial atherosclerotic stenosis or occlusion at Seoul National University Hospital. Background Introduction: Intracranial atherosclerotic disease (ICAD) causing stenosis or occlusion is one of the major causes leading to ischemi...

In this academic paper, the authors attempt to address the common headache complication during magnetic resonance-guided focused ultrasound (mrgFUS) treatment. Headache is a common complication, and in severe cases, it may even cause patients to be unable to tolerate ultrasound radiation and terminate the treatment. There is currently no establishe...