Report on the Study of the Impact of ANCV1R Gene Deficiency on Pheromone Detection and Sexual Behavior in Mice Background Introduction In mammals, pheromones are crucial chemical signals that regulate social and sexual behaviors. Pheromone detection is mediated by the vomeronasal organ (VNO), which uses vomeronasal sensory neurons (VSNs) to recogni...
Diffusion-Based Feature Augmentation: A Novel Approach for Multiple Instance Learning in Whole Slide Images Academic Background and Research Motivation In computational pathology, effectively analyzing Whole Slide Images (WSIs) is a burgeoning area of research. WSIs are ultra-high-resolution images with a broad field of view and are widely employed...
Innovative Advances in Wearable Single-Transducer Echomyography Systems: From Muscle Dynamics Monitoring to Complex Gesture Tracking Academic Background and Research Significance In recent years, wearable electronic devices have garnered significant attention for their enormous potential in health monitoring and human-machine interaction. Electromy...
Digitally Embroidered Metamaterial Biosensor: Non-Contact Physiological Monitoring in Dynamic Environments Recent years have witnessed rapid development of sensor technologies driven by demands in smart vehicles, aviation safety, and health monitoring. However, for physiological signal detection in dynamic environments, traditional sensors face sig...
Repeated Exposure to Sevoflurane Impairs GABAergic Neuronal Development and Social Cognitive Function in the Hippocampal CA2 Region of Mice Academic Background Approximately 1.5 million infants and young children undergo medical procedures requiring general anesthesia annually, with sevoflurane being widely used in pediatric anesthesia. However, in...
Personalized Perioperative Dosing of Ivabradine in Noncardiac Surgery: A Single-Centre, Randomised, Placebo-Controlled, Double-Blind Feasibility Pilot Trial Academic Background Perioperative myocardial injury (PMI) is a common complication following noncardiac surgery and is closely associated with postoperative mortality and morbidity. Studies hav...
Lifetime Risk of Surgery in England: A Nationwide Observational Cohort Study Academic Background Surgery represents a significant portion of the UK National Health Service (NHS) activity, with approximately 4.4 million people undergoing surgical procedures in England each year. Although an increasing number of surgeries are performed as day-case pr...
In the field of anesthesiology, propofol is a widely used intravenous anesthetic, and its pharmacokinetic (PK) and pharmacodynamic (PD) models are crucial for precise control of anesthetic depth. The Eleveld model is a widely applied PK-PD model for propofol, capable of predicting propofol plasma concentrations, effect-site concentrations, and the ...
Effects of Inhalation versus Total Intravenous Anaesthesia on Long-Term Mortality in Older Patients after Noncardiac Surgery: A Retrospective Observational Study Academic Background With the global aging phenomenon, the number of elderly patients undergoing surgery is increasing year by year. Elderly patients are more susceptible to adverse effects...
Distribution and Outcomes of Paediatric Anaesthesia Services in Sweden: An Epidemiological Study Academic Background In recent years, there has been a growing trend towards the centralization of perioperative care for children globally, particularly in European countries. This trend is primarily driven by research findings from professional organiz...