Academic Background Prostate cancer is one of the most common cancers in men worldwide, particularly in Western countries. Despite advances in early diagnosis and treatment significantly improving survival rates, cancer recurrence remains a major clinical challenge. This is particularly true for patients with high-risk nonmetastatic hormone-sensiti...

Report on the Association Between Prenatal Exposure to Systemic Glucocorticoids and Offspring Mental Disorders Academic Background Glucocorticoids are widely used among pregnant women, particularly those at high risk of preterm birth or with autoimmune disorders. These treatments can reduce neonatal morbidity and mortality or alleviate symptoms by ...

Systematic Review of Mortality Risk Prediction Models for Patients with Kidney Failure Academic Background Kidney failure is a severe chronic condition, with a significant decline in both quality of life and survival rates compared to patients with other chronic diseases, including some forms of non-metastatic cancer. Patients with kidney failure o...

Report on the Management of Chinese Older Adults with Type 2 Diabetes through Couple-Based Interventions: A Randomized Clinical Trial Academic Background Type 2 Diabetes Mellitus (T2DM) is one of the most prevalent chronic diseases globally, particularly common among older adults. China has the largest number of diabetes patients worldwide, reachin...

Comparative Analysis of Recombinant Quadrivalent Influenza Vaccine and Standard Egg-Based Quadrivalent Influenza Vaccine in Nursing Home Residents: A Cluster Randomized Trial Academic Background Influenza is among the primary respiratory pathogens causing morbidity and mortality among the elderly worldwide, particularly in nursing home residents wh...

A Systematic Review and Meta-Analysis of Glutamatergic Medications for Obsessive-Compulsive and Related Disorders (OCRDs) Academic Context Obsessive-Compulsive and Related Disorders (OCRDs) represent a group of neuropsychiatric conditions characterized by excessive, persistent obsessions or compulsions. These disorders include Obsessive-Compulsive ...

Academic Paper Report Caries is one of the most common chronic diseases in children, with significant health disparities across racial, ethnic, and income groups. Despite the availability of effective preventive measures, children from low-income and minority ethnic groups continue to face higher risks of caries. The American Academy of Pediatrics ...

Economic Evaluation of Breast Cancer Screening: A Study Based on Digital Mammography in Canada Academic Background Breast cancer (BC) is one of the most commonly diagnosed cancers in women and the second leading cause of cancer-related deaths in North America. Although significant progress has been made in breast cancer treatment over the past deca...

Association of CHEK2 Low-Risk Variants with Cancer Phenotypes Academic Background The CHEK2 gene (OMIM 604373) is one of the susceptibility genes for breast cancer. Monoallelic pathogenic variants (PVs) in CHEK2 are associated with an increased risk of breast, colorectal, kidney, and thyroid cancers. However, there is limited research on the phenot...

Academic Context and Problem Statement Age-related macular degeneration (AMD) is one of the leading causes of vision loss in many high-income countries. Among its forms, neovascular AMD (also known as wet AMD) can be associated with submacular hemorrhage (SMH), a rare but severe condition. If untreated, SMH can lead to significant vision loss. Anti...