The Utility of GPT-4 in Chest Radiograph Evaluation

The Potential of GPT-4 in Chest Radiograph Evaluation: A Retrospective Study Academic Background In recent years, artificial intelligence (AI) has been increasingly applied in the medical field, particularly in radiology. The introduction of AI tools is transforming clinical practice, especially in imaging diagnostics. However, the widespread adopt...

Quantitative Assessment of GPT-4V’s Multimodal and Multianatomic Region Capabilities in Radiology

Quantitative Assessment of Large Vision-Language Models in Radiology: GPT-4V’s Multimodal and Multi-Anatomic Region Capabilities Academic Background In recent years, large language models (LLMs) such as OpenAI’s ChatGPT have made significant progress in text generation. These models, based on the Transformer architecture and trained on massive amou...

Diagnostic Accuracy of CT for the Detection of Hepatic Steatosis: A Systematic Review and Meta-Analysis

Diagnostic Accuracy of CT for the Detection of Hepatic Steatosis: A Systematic Review and Meta-Analysis Academic Background Hepatic steatosis is the result of the abnormal accumulation of triglycerides in hepatocytes, which can initiate a cascade of inflammatory responses, referred to as steatotic liver disease (SLD). Metabolic dysfunction–associat...

Assessment of Nonmass Lesions Detected with Screening Breast US Based on Mammographic Findings

Assessment of Nonmass Lesions Detected with Screening Breast US Based on Mammographic Findings Academic Background Breast cancer is one of the most common malignant tumors among women worldwide, and early detection and diagnosis are crucial for improving patient survival rates. Breast ultrasound (US), as a non-invasive and radiation-free imaging mo...

The Role of lncRNA-Mediated ceRNA Network in Penile Squamous Cell Carcinoma

The Role of lncRNA-Mediated ceRNA Network in Penile Squamous Cell Carcinoma Academic Background Penile Squamous Cell Carcinoma (PSCC) is a relatively rare but life-threatening malignancy that poses a significant health risk to men, particularly in developing countries. Despite advancements in medical diagnosis and treatment, the overall survival ra...

Combined Single Cell and Spatial Transcriptome Analysis Reveals Cellular Heterogeneity of Hedgehog Pathway in Gastric Cancer

Combined Single-Cell and Spatial Transcriptome Analysis Reveals Cellular Heterogeneity of the Hedgehog Pathway in Gastric Cancer Academic Background Gastric cancer (GC) is one of the most common and deadly malignancies worldwide, with high incidence and mortality rates. Despite advancements in chemotherapy, radiotherapy, and targeted therapy, the t...

A Potential Coagulation-Related Diagnostic Model Associated with Immune Infiltration for Acute Myocardial Infarction

Potential Coagulation-Related Diagnostic Model Associated with Immune Infiltration for Acute Myocardial Infarction Academic Background Acute Myocardial Infarction (AMI) is one of the leading causes of death worldwide. Despite significant advancements in diagnosis, treatment, and prognosis in recent years, the incidence and mortality rates of AMI re...

Myeloid Derived Suppressor Cells Mediate Hepatocyte Proliferation and Immune Suppression During Liver Regeneration Following Resection

Academic Background Liver regeneration is a complex biological process involving the coordinated action of various cell types and signaling pathways. Following partial liver resection, the remaining liver tissue restores its function and mass through a series of precisely regulated cell proliferation and immune responses. Although extensive researc...

Regulatory T Cells-Related Gene in Primary Sclerosing Cholangitis: Evidence from Mendelian Randomization and Transcriptome Data

Regulatory T Cells-Related Gene in Primary Sclerosing Cholangitis: Evidence from Mendelian Randomization and Transcriptome Data Authors: Jianlan Hu1, Youxing Wu1, Danxia Zhang1, Xiaoyang Wang1, Yaohui Sheng1, Hui Liao1, Yangpeng Ou2✉, Zhen Chen3, Baolian Shu1✉, and Ruohu Gui1✉ Journal: Genes & Immunity (2024) 25:492–513 DOI: https://doi.org/10.1038...

Neoantigen-Specific mRNA/DC Vaccines for Effective Anticancer Immunotherapy

Effectiveness of Neoantigen-Specific mRNA/DC Vaccines in Anticancer Immunotherapy Academic Background Cancer immunotherapy has emerged as a significant breakthrough in cancer treatment in recent years. Among the various approaches, dendritic cell (DC) vaccines have shown potential in extending the survival of some advanced cancer patients. However,...