Academic News Report: The Temporal and Spatial Bias in β-arrestin Signal Transduction Mediated by G Protein-Coupled Receptor Endocytosis Research Background Among cell surface receptor families, G protein-coupled receptors (GPCRs) constitute the largest family. Upon activation by ligands, they interact with various signaling proteins to trigger int...
Research Report on Multi-sensory Flicker Regulating Extensive Brain Networks and Reducing Interictal Epileptiform Discharges Background Introduction In treating neurological disorders, modulating brain oscillations has great potential. Non-invasive interventions, suitable for everyday use at home, have become the focus of the scientific community, ...
Electrophysiological Signatures of Veridical Head Direction in Humans Navigation is one of the core components of human complex cognition, where head direction information is crucial for positioning oneself in space. However, due to the requirement of having the head fixed in a specific position during most neuroimaging experiments, understanding h...
Study on the Differences in Cortical Layers During Epileptic Seizure Onset and Spread Epilepsy is a neurological disorder that severely impacts patients’ quality of life, affecting approximately 1% of the global population. Among all epilepsy patients, nearly one-third are resistant to pharmaceutical treatments, known as drug-resistant epilepsy. Fo...
Alzheimer’s Disease Research and Treatment Frontiers: Beta/Theta Power Ratio in EEG Periodic Components as a Potential Biomarker Background Introduction Alzheimer’s dementia (AD) is a progressively developing disease, accounting for 60% to 80% of all dementia cases [1]. In the early stages of AD, mild cognitive impairment (MCI) typically occurs, du...
Modulation of P3m Amplitude by Task Difficulty in a Visual Oddball Task Background In cognitive neuroscience research, Event-Related Potentials (ERP) and Event-Related Fields (ERF) are important means to explore the cognitive processing mechanisms of the brain. Among these, the P3 component (referred to as P3m in magnetoencephalography) has garnere...
Enhancement of Theta and Alpha Oscillations Prior to Crossmodal Memory Encoding Background Episodic memory is a crucial component of human memory, with one of its core mechanisms being the formation of associations through stimuli from different sensory channels. Current theories suggest that during crossmodal associative encoding, the phase and po...
Study on the Relationship between Macroscopic Intrinsic Dynamics and Microcircuit Functions in Epilepsy Research Background Epilepsy is a group of neurological disorders characterized by abnormal spontaneous brain activity, involving multi-scale changes in brain functional organization. However, it remains unclear to what extent epilepsy-related sp...
Research Report on Changes in Functional Connectivity in Post-Stroke Epilepsy (PSE) Patients Based on Source-Level EEG and Graph Theory Research Background Epilepsy has various etiologies, including idiopathic, congenital, head trauma, central nervous system infections, brain tumors, neurodegenerative diseases, and cerebrovascular diseases. Among t...
Research Report on the Integration of Medical Relation Extraction and Knowledge Graph-Based Recommendations Background Introduction In the medical field, the explosive growth of literature makes it challenging for researchers to keep up with the latest advancements in their specific areas. From the perspective of natural language processing (NLP), ...