Revealing the Neuromechanism of Interhemispheric Balance Restoration in Chronic Stroke Patients through EMG-driven Robot Hand Training: Insights from Dynamic Causal Modeling Stroke is a common cause of disability, with most stroke survivors suffering from upper limb paralysis. The consequences of upper limb functional impairment can persist for ove...

Brain-Computer Interface (BCI) technology has rapidly developed in recent years and is considered a cutting-edge technology that allows external devices to be controlled directly by the brain without the need for peripheral nerves and muscles. Particularly in the application of Motor Imagery Electroencephalography (MI-EEG), BCI technology has shown...

Phase-Dependent Language Perception in Neural Oscillations: An Interdisciplinary Study Report Background During speech perception, the phase of neural oscillations plays a crucial role in the separation of neural representations and perceptual decisions. However, the specific phase-encoding mechanisms remain unclear. This study aims to reveal how p...

Human Sensorimotor Resting State β Events and Aperiodic Activity Exhibit Good Test-Retest Reliability Background Neurological diseases are some of the most impactful diseases on daily human life, particularly those affecting sensory and motor functions, such as Parkinson’s disease. Early diagnosis of these diseases is often exceedingly difficult du...

Temporal and Spatial Dynamics of Somatosensory Cortex Network in Typically Developing Children Research Background Touch plays a crucial role in our interaction with external objects and the fine control of hand movements. Despite substantial research on the mechanisms of sensory information processing in human skin, it remains unclear how brain re...

Systematic Analysis of NDUFAF6 in Complex I Assembly and Mitochondrial Disease Background Mitochondrial complex I (CI) is a crucial component of the respiratory chain, playing an essential role in oxidative phosphorylation (OXPHOS) by introducing electrons into the mitochondrial respiratory chain and, together with complexes II-IV, generating and m...

Unsaturation of Fatty Acids Promotes Pore-Forming Activity of Bax and Bak in Apoptosis Background Apoptosis is the major form of programmed cell death, involved in fundamental biological processes such as embryonic development, tissue homeostasis, and immune system functions. Dysregulation of apoptosis can lead to neurodegenerative diseases and tum...

Orthogonal Proteogenomic Analysis Identifies Druggable PA2G4-MYC Axis in 3q26 AML Acute myeloid leukemia (AML) is a highly heterogeneous and aggressive malignancy. In particular, the 3q26 chromosomal abnormality subtype of AML has a complex pathogenic mechanism and lacks effective targeted therapies. To address this challenge, Matteo Marchesini and...

This paper aims to explore the physiological importance of glycolysis in neuronal metabolic processes. For a long time, although neuronal activity mainly relies on glucose for energy, neurons have relatively weak glucose metabolism, mainly through glycolysis rather than other metabolic pathways. This phenomenon can be attributed to the sustained de...

Differential Effects of Exercise Timing on Skeletal Growth in Mice Introduction Skeletal growth is crucial for adult height and bone health. Studies have shown that exercise can effectively increase bone density, but the optimal exercise timing remains unclear. This study aimed to investigate the optimal exercise timing by comparing the effects of ...