Multi-scale and Multi-level Feature Assessment Framework for Classification of Parkinson’s Disease State from Short-term Motor Tasks

Academic Background Parkinson’s Disease (PD) is the second most common chronic neurodegenerative disease, primarily affecting individuals aged 65 and above. With the global population aging, the prevalence of Parkinson’s disease is projected to increase from 7 million in 2015 to 13 million by 2040. Currently, the diagnosis of Parkinson’s disease ma...

A Quantitative Comparison of Electrode Positions for Respiratory Surface EMG

A Quantitative Comparison Study of Electrode Positions for Respiratory Surface Electromyography Academic Background Respiratory surface electromyography (SEMG) is a non-invasive technique used to record the electrical activity of respiratory muscles. It is widely applied in analyzing respiratory effort, patient-ventilator asynchrony, and respirator...

Multi-Material Decomposition Using Spectral Diffusion Posterior Sampling

Multi-Material Decomposition Research Based on Spectral Diffusion Posterior Sampling Background Introduction In the field of medical imaging, CT (Computed Tomography) technology is widely used in disease diagnosis and treatment planning. In recent years, spectral CT has become a research hotspot due to its ability to provide energy-dependent attenu...

Deep Reconstruction Framework with Self-Calibration Mechanisms for Accelerated Chemical Exchange Saturation Transfer Imaging

Application of the Deep Reconstruction Framework with Self-Calibration Mechanisms (DEISM) in Accelerated Chemical Exchange Saturation Transfer Imaging Academic Background Chemical Exchange Saturation Transfer (CEST) imaging is a highly sensitive molecular magnetic resonance imaging technique capable of detecting biomolecules associated with various...

Heart Rate and Body Temperature Relationship in Children Admitted to PICU - A Machine Learning Approach

Machine Learning Study on the Relationship Between Heart Rate and Body Temperature in Pediatric Intensive Care Units Academic Background In the pediatric intensive care unit (PICU), heart rate (HR) and body temperature (BT) are crucial clinical indicators that reflect a patient’s physiological status. Although the relationship between HR and BT has...

Self-Supervised Feature Detection and 3D Reconstruction for Real-Time Neuroendoscopic Guidance

Self-Supervised Feature Detection and 3D Reconstruction for Real-Time Neuroendoscopic Guidance

Research on Real-Time 3D Reconstruction and Navigation in Neuroendoscopy Based on Self-Supervised Learning Academic Background Neuroendoscopic surgery, as a minimally invasive surgical technique, is widely used in the treatment of deep brain lesions, such as endoscopic third ventriculostomy (ETV), choroid plexus cauterization, and cyst fenestration...

Ketones in Cellular Physiology: Metabolic, Signaling, and Therapeutic Advances

Research Report: The Role of Ketones in Cellular Physiology: Metabolic, Signaling, and Therapeutic Advances Academic Background For a long time, carbohydrate (CHO) intake has been considered a key factor in enhancing athletic performance during endurance exercise. The traditional view holds that a high-carbohydrate low-fat diet (HCLF) can increase ...

The Role of KV7 Channels in Modulating Tension and Calcium Signaling in Mouse Corpus Cavernosum

Study on the Role of KV7 Channels in Regulating Smooth Muscle Contraction in Mouse Corpus Cavernosum Academic Background Erectile dysfunction (ED) is a significant health issue that impacts the quality of life for men. Since the introduction of phosphodiesterase 5 (PDE5) inhibitors like Sildenafil in the 1990s, there has been notable progress in th...

Estrogen Deficiency Alters Vascularization and Mineralization Dynamics: Insight from a Novel 3-D Humanized and Vascularized Bone Organoid Model

The Impact of Estrogen Deficiency on Vascularization and Mineralization Dynamics—Insights from a Novel 3D Humanized and Vascularized Bone Organoid Model Academic Background Osteoporosis is a common bone disease, particularly prevalent among postmenopausal women. Osteoporosis not only manifests as a reduction in bone mass but also involves changes i...

CDC42 is crucial for the early regulation of hepatic stellate cell activation

CDC42 Plays a Crucial Role in the Early Regulation of Hepatic Stellate Cell Activation Academic Background Liver fibrosis is a pathological process associated with various liver diseases, which may eventually progress to cirrhosis—a life-threatening condition. Currently, there are no effective treatments to halt the progression of liver fibrosis. H...